tetano
Editor, Senior Moderator
Ann Med Surg (Lond)
. 2021 Nov;71:102946.
doi: 10.1016/j.amsu.2021.102946. Epub 2021 Oct 14.
Transformation of acute cholecystitis to acute choledocholithiasis in COVID-19 patient
David Song[SUP] 1 [/SUP], Harinivaas Shanmugavel Geetha[SUP] 2 [/SUP], Andrew Kim[SUP] 3 [/SUP], Tasur Seen[SUP] 1 [/SUP], Talal Almas[SUP] 4 [/SUP], Vikneswaran Raj Nagarajan[SUP] 4 [/SUP], Noor Alsaeed[SUP] 4 [/SUP], Jui Hsin Cheng[SUP] 4 [/SUP], Joseph Lieber[SUP] 1 [/SUP]
Affiliations
Abstract
The global pandemic of Coronavirus 2019 (COVID-19) or SARS-CoV-2 has numerous manifestations in different organ systems. It is known that SARS-CoV-2 infects the hepatobiliary system leading to presentations such as acute cholecystitis, choledocholithiasis and hepatitis. Although the exact mechanism of the underlying pathology is unknown, it is likely attributed by the tropism of the virus to the ACE2 receptors in the hepatocytes and bile duct cells resulting in a cytokine storm that precipitates as systemic symptoms from acute COVID-19 infection. In this case report we present a case of a 47-year-old male who presented with signs consistent with acute cholecystitis. It was confirmed on ultrasound and he was incidentally found to be positive for COVID-19 on routine surveillance testing. He was asymptomatic and was being prepped for cholecystectomy, but developed an acute elevation of liver enzymes suggesting choledocholithiasis. After endoscopic retrograde cholangiopancreatography (ERCP) and cholecystectomy the patient experienced a rapid normalization of liver enzymes and improvement of his abdominal symptoms.
Keywords: COVID-19; Cholecystitis; Cholidocolithais; Coronavirus 2019; SARS-CoV-2.
. 2021 Nov;71:102946.
doi: 10.1016/j.amsu.2021.102946. Epub 2021 Oct 14.
Transformation of acute cholecystitis to acute choledocholithiasis in COVID-19 patient
David Song[SUP] 1 [/SUP], Harinivaas Shanmugavel Geetha[SUP] 2 [/SUP], Andrew Kim[SUP] 3 [/SUP], Tasur Seen[SUP] 1 [/SUP], Talal Almas[SUP] 4 [/SUP], Vikneswaran Raj Nagarajan[SUP] 4 [/SUP], Noor Alsaeed[SUP] 4 [/SUP], Jui Hsin Cheng[SUP] 4 [/SUP], Joseph Lieber[SUP] 1 [/SUP]
Affiliations
- PMID: 34664016
- PMCID: PMC8514612
- DOI: 10.1016/j.amsu.2021.102946
Abstract
The global pandemic of Coronavirus 2019 (COVID-19) or SARS-CoV-2 has numerous manifestations in different organ systems. It is known that SARS-CoV-2 infects the hepatobiliary system leading to presentations such as acute cholecystitis, choledocholithiasis and hepatitis. Although the exact mechanism of the underlying pathology is unknown, it is likely attributed by the tropism of the virus to the ACE2 receptors in the hepatocytes and bile duct cells resulting in a cytokine storm that precipitates as systemic symptoms from acute COVID-19 infection. In this case report we present a case of a 47-year-old male who presented with signs consistent with acute cholecystitis. It was confirmed on ultrasound and he was incidentally found to be positive for COVID-19 on routine surveillance testing. He was asymptomatic and was being prepped for cholecystectomy, but developed an acute elevation of liver enzymes suggesting choledocholithiasis. After endoscopic retrograde cholangiopancreatography (ERCP) and cholecystectomy the patient experienced a rapid normalization of liver enzymes and improvement of his abdominal symptoms.
Keywords: COVID-19; Cholecystitis; Cholidocolithais; Coronavirus 2019; SARS-CoV-2.