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Ann Med Surg (Lond) . Co-infection of SARS-CoV-2 with other viral respiratory pathogens in Yogyakarta, Indonesia: A cross-sectional study

tetano

Editor, Senior Moderator
Ann Med Surg (Lond)


. 2022 May;77:103676.
doi: 10.1016/j.amsu.2022.103676. Epub 2022 Apr 30.
Co-infection of SARS-CoV-2 with other viral respiratory pathogens in Yogyakarta, Indonesia: A cross-sectional study


Eggi Arguni[SUP] 1 [/SUP], Endah Supriyati[SUP] 2 3 [/SUP], Mohamad Saifudin Hakim[SUP] 4 [/SUP], Edwin Widyanto Daniwijaya[SUP] 4 [/SUP], Firdian Makrufardi[SUP] 1 [/SUP], Ayu Rahayu[SUP] 2 3 [/SUP], Anwar Rovik[SUP] 2 3 [/SUP], Utari Saraswati[SUP] 2 3 [/SUP], Farida Nur Oktoviani[SUP] 4 [/SUP], Nenes Prastiwi[SUP] 4 [/SUP], Titik Nuryastuti[SUP] 4 [/SUP], Tri Wibawa[SUP] 4 [/SUP], Sofia Mubarika Haryana[SUP] 5 [/SUP]



Affiliations

Abstract

Background: Growing evidence shows that viral co-infection is found repeatedly in patients with Coronavirus Disease-2019 (COVID-19). This is the first report of SARS-CoV-2 co-infection with viral respiratory pathogens in Indonesia.
Methods: Over a one month period of April to May 2020, SARS-CoV-2 positive nasopharyngeal swabs in our COVID-19 referral laboratory in Yogyakarta, Indonesia, were tested for viral respiratory pathogens by real-time, reverse transcription polymerase chain reaction (RT-PCR). Proportion of co-infection reported in percentage.
Results: Fifty-nine samples were positive for other viral respiratory pathogens among a total of 125 samples. Influenza A virus was detected in 32 samples, Influenza B in 16 samples, Human metapneumovirus in 1 sample, and adenovirus in 10 samples. We did not detect any co-infection with respiratory syncytial virus. Nine (7.2%) patients had co-infection with more than two viruses.
Conclusion: Viral co-infection with SARS-CoV-2 is common. These results will provide a helpful reference for diagnosis and clinical treatment of patients with COVID-19.

Keywords: COVID-19; Co-infection; Coronavirus; SARS-CoV-2; Viral respiratory pathogens.
 
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