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Ann Epidemiol . Association between Cardiovascular Risk and Coronavirus Disease 2019: Findings from 2021 National Health Interview Survey

tetano

Editor, Senior Moderator
Ann Epidemiol


. 2023 Mar 22;S1047-2797(23)00054-6.
doi: 10.1016/j.annepidem.2023.03.005. Online ahead of print.
Association between Cardiovascular Risk and Coronavirus Disease 2019: Findings from 2021 National Health Interview Survey


Longjian Liu[SUP] 1 [/SUP], Nathalie S May[SUP] 2 [/SUP], Priscila Y Sato[SUP] 3 [/SUP], Paakhi Srivastava[SUP] 4 [/SUP], Leslie A McClure[SUP] 5 [/SUP]



Affiliations
Free PMC article

Abstract

Purpose: To examine the association between pre-existing cardiovascular disorders and the risk of coronavirus disease 2019 (COVID-19) among community-dwelling adults in the United States (US).
Methods: We analyzed data from the 2021 National Health Interview Survey (NHIS), encompassing 28,848 nationally representative participants aged ≥18. We examined the association by two age groups, younger adults (aged 18-59) and older adults (aged>60). Weighted analyses were conducted to consider the complex sampling design used in the NHIS.
Results: Our results show that 13.9% of younger and 8.2% of older adults were infected with coronavirus, corresponding to a nationwide estimate of 23,701,358 COVID-19 cases in younger adults and 6,310,206 in older adults in 2021. Subjects who lived in the South region of the US had the highest COVID-19 rate (13.4%), followed by the Midwest (12.6%), West (10.9%), and Northeast (10.4%). Pre-existing cardiovascular risk factors (overweight, obesity, hypertension, and diabetes) were significantly associated with increased risk for COVID-19 infection in younger and older adults. Pre-existing cardiovascular diseases (angina, heart attack, and coronary heart disease) were significantly associated with COVID-19 in older adults but not significantly in younger adults. Significant dose-response relationships existed between the increased number of pre-existing cardiovascular risk factors and COVID-19 infection, with the strongest association in non-Hispanic (NH) Black and Hispanic ethnicities compared to NH White.
Conclusion: Pre-existing cardiovascular disorders are significantly associated with the risk of COVID-19 infection. The magnitudes of this risk association are stronger among the minority populations than NH White. Further studies are needed to determine the long-term impact of COVID-19 infection and its relationship to pre-existing cardiovascular disorders.
 
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