tetano
Editor, Senior Moderator
Ann Dermatol
. 2023 Nov;35(Suppl 2):S281-S286.
doi: 10.5021/ad.21.307. Cases of Pernio-Like Lesions after mRNA-1273 Vaccination with Clinical and Pathological Features: A Single-Center Experience
Young-Wook Ryoo[SUP] 1 [/SUP], Ji-Min Yun[SUP] 1 [/SUP], Hyun-Wook Kim[SUP] 1 [/SUP], Hye Won Lee[SUP] 2 [/SUP], Hye Ra Jung[SUP] 2 [/SUP], Sung-Ae Kim[SUP] 3 [/SUP]
Affiliations
The currently available coronavirus disease 2019 (COVID-19) vaccines in South Korea include mRNA (Moderna[SUP]®[/SUP] and Pfizer[SUP]®[/SUP]) and adenoviral vector (AstraZeneca[SUP]®[/SUP] and Janssen[SUP]®[/SUP]) vaccines. Dermatologic side effects of COVID-19 vaccines range from local injection site reactions to systemic eruptions, including morbilliform rashes or erythema multiforme. Pernio-like lesions, one of the most common cutaneous manifestations of COVID-19, have been rarely reported post-vaccination. Herein, we report four cases of pernio-like lesions, which were detected in a single tertiary hospital within 2 months, after the first dose of mRNA-1273 (Moderna[SUP]®[/SUP]) vaccination was administered. In this study, we discuss the clinical and pathological features of our cases and compare them with those of previously reported cases of pernio-like lesions after COVID-19 vaccination. It is pivotal to realize that perniolike lesions can be a possible side effect of COVID-19 vaccination and that the number of patients experiencing this side effect is bound to be quite high in real-world clinical settings.
Keywords: Adverse drug reactions; COVID-19; Chilblains; mRNA-1273.
. 2023 Nov;35(Suppl 2):S281-S286.
doi: 10.5021/ad.21.307. Cases of Pernio-Like Lesions after mRNA-1273 Vaccination with Clinical and Pathological Features: A Single-Center Experience
Young-Wook Ryoo[SUP] 1 [/SUP], Ji-Min Yun[SUP] 1 [/SUP], Hyun-Wook Kim[SUP] 1 [/SUP], Hye Won Lee[SUP] 2 [/SUP], Hye Ra Jung[SUP] 2 [/SUP], Sung-Ae Kim[SUP] 3 [/SUP]
Affiliations
- PMID: 38061722
- DOI: 10.5021/ad.21.307
The currently available coronavirus disease 2019 (COVID-19) vaccines in South Korea include mRNA (Moderna[SUP]®[/SUP] and Pfizer[SUP]®[/SUP]) and adenoviral vector (AstraZeneca[SUP]®[/SUP] and Janssen[SUP]®[/SUP]) vaccines. Dermatologic side effects of COVID-19 vaccines range from local injection site reactions to systemic eruptions, including morbilliform rashes or erythema multiforme. Pernio-like lesions, one of the most common cutaneous manifestations of COVID-19, have been rarely reported post-vaccination. Herein, we report four cases of pernio-like lesions, which were detected in a single tertiary hospital within 2 months, after the first dose of mRNA-1273 (Moderna[SUP]®[/SUP]) vaccination was administered. In this study, we discuss the clinical and pathological features of our cases and compare them with those of previously reported cases of pernio-like lesions after COVID-19 vaccination. It is pivotal to realize that perniolike lesions can be a possible side effect of COVID-19 vaccination and that the number of patients experiencing this side effect is bound to be quite high in real-world clinical settings.
Keywords: Adverse drug reactions; COVID-19; Chilblains; mRNA-1273.