tetano
Editor, Senior Moderator
Animals (Basel)
. 2021 Dec 8;11(12):3506.
doi: 10.3390/ani11123506.
Myocardial Injury Complicated by Systolic Dysfunction in a COVID-19-Positive Dog
Giovanni Romito[SUP] 1 [/SUP], Teresa Bertaglia[SUP] 2 [/SUP], Luigi Bertaglia[SUP] 2 [/SUP], Nicola Decaro[SUP] 3 [/SUP], Annamaria Uva[SUP] 3 [/SUP], Gianluca Rugna[SUP] 4 [/SUP], Ana Moreno[SUP] 4 [/SUP], Giacomo Vincifori[SUP] 5 [/SUP], Francesco Dondi[SUP] 1 [/SUP], Alessia Diana[SUP] 1 [/SUP], Mario Cipone[SUP] 1 [/SUP]
Affiliations
Abstract
A six-year-old Cavalier King Charles spaniel was referred with a two-month history of severe exercise intolerance and syncope. Clinical signs had developed during a local wave of coronavirus disease (COVID-19) two weeks after its family members had manifested symptoms of this viral disease and their positivity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed. Cardiologic assessment documented myocardial injury complicated by systolic dysfunction. An extensive diagnostic work-up allowed us to rule out common causes of myocardial compromise, both infective and not. Accordingly, serological and molecular tests aimed at diagnosing SARS-CoV-2 infection were subsequently performed, especially in light of the dog's peculiar history. Results of such tests, interpreted in the light of previous findings and current knowledge from human medicine, supported a presumptive diagnosis of COVID-19-associated myocardial injury, a clinical entity hitherto poorly described in this species.
Keywords: SARS-CoV-2; canine; dilated cardiomyopathy phenotype; echocardiography; myocarditis.
. 2021 Dec 8;11(12):3506.
doi: 10.3390/ani11123506.
Myocardial Injury Complicated by Systolic Dysfunction in a COVID-19-Positive Dog
Giovanni Romito[SUP] 1 [/SUP], Teresa Bertaglia[SUP] 2 [/SUP], Luigi Bertaglia[SUP] 2 [/SUP], Nicola Decaro[SUP] 3 [/SUP], Annamaria Uva[SUP] 3 [/SUP], Gianluca Rugna[SUP] 4 [/SUP], Ana Moreno[SUP] 4 [/SUP], Giacomo Vincifori[SUP] 5 [/SUP], Francesco Dondi[SUP] 1 [/SUP], Alessia Diana[SUP] 1 [/SUP], Mario Cipone[SUP] 1 [/SUP]
Affiliations
- PMID: 34944281
- DOI: 10.3390/ani11123506
Abstract
A six-year-old Cavalier King Charles spaniel was referred with a two-month history of severe exercise intolerance and syncope. Clinical signs had developed during a local wave of coronavirus disease (COVID-19) two weeks after its family members had manifested symptoms of this viral disease and their positivity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed. Cardiologic assessment documented myocardial injury complicated by systolic dysfunction. An extensive diagnostic work-up allowed us to rule out common causes of myocardial compromise, both infective and not. Accordingly, serological and molecular tests aimed at diagnosing SARS-CoV-2 infection were subsequently performed, especially in light of the dog's peculiar history. Results of such tests, interpreted in the light of previous findings and current knowledge from human medicine, supported a presumptive diagnosis of COVID-19-associated myocardial injury, a clinical entity hitherto poorly described in this species.
Keywords: SARS-CoV-2; canine; dilated cardiomyopathy phenotype; echocardiography; myocarditis.