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Analysis of HA and NA Genes of Influenza A H1N1 Virus in Yunnan Province during 2009-2014

tetano

Editor, Senior Moderator
Bing Du Xue Bao. 2015 Nov;31(6):674-8.
[Analysis of HA and NA Genes of Influenza A H1N1 Virus in Yunnan Province during 2009-2014].

[Article in Chinese]
Li J, Zhao X, Cao Y, Ning D, Fu X, Xu W.
Abstract

To analyze influenza pathogen spectrum in Yunnan province during 2009-2014 years, and analyze HA and NA genes of influenza A H1N1. Analysis was made on the monitoring date of influenza cases in Yunnan province in recent 6 years, 23 strains of influenza virus of HA and NA gene was sequenced and analyzed by MEGA 5 software to construct phylogenetic tree. 4 times of influenza AH1N1 epidemic peak were monitored from 2009-2014 years in Yunnan Province, as the nucleic acid detection results of influenza A H1N1 accounted for 28.8% of the total. The sequencing result showed that HA and NA gene were divided into 3 groups, one was detected with H275Y mutation strains. Influenza A H1N1 is one of the important subtypes in Yunnan province and their genes have divided into three branches during the period of 2009-2014 years, the vast majority of influenza a H1N1 are still sensitive to neuraminidase inhibitors.


PMID: 26951014 [PubMed - in process]
 
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