tetano
Editor, Senior Moderator
Anal Methods
. 2024 Jan 17.
doi: 10.1039/d3ay01825c. Online ahead of print. Highly reproducible electrochemical biosensor for Influenza A virus towards low-resource settings
Julio Ojeda[SUP] 1 [/SUP], Fiorella Torres-Salvador[SUP] 1 [/SUP], Nicholas Bruno[SUP] 1 [/SUP], Hannah Eastwood[SUP] 1 [/SUP], Yulia Gerasimova[SUP] 1 [/SUP], Karin Chumbimuni-Torres[SUP] 1 [/SUP]
Affiliations
A highly reproducible electrochemical biosensor, employing a five-stranded four-way junction (5S-4WJ) system through square wave voltammetry, has been successfully validated for the detection of Influenza A virus (InfA). A comprehensive assessment of its linearity, precision, accuracy, and robustness has demonstrated its compliance with FDA standards. Integration with Nucleic Acid-Based Amplification (NASBA) has showcased its selectivity for InfA, enabling the detection of InfA RNA with a standard heater set at 41 °C. This platform offers a straightforward setup well-suited for use at low-resource facilities.
. 2024 Jan 17.
doi: 10.1039/d3ay01825c. Online ahead of print. Highly reproducible electrochemical biosensor for Influenza A virus towards low-resource settings
Julio Ojeda[SUP] 1 [/SUP], Fiorella Torres-Salvador[SUP] 1 [/SUP], Nicholas Bruno[SUP] 1 [/SUP], Hannah Eastwood[SUP] 1 [/SUP], Yulia Gerasimova[SUP] 1 [/SUP], Karin Chumbimuni-Torres[SUP] 1 [/SUP]
Affiliations
- PMID: 38230437
- DOI: 10.1039/d3ay01825c
A highly reproducible electrochemical biosensor, employing a five-stranded four-way junction (5S-4WJ) system through square wave voltammetry, has been successfully validated for the detection of Influenza A virus (InfA). A comprehensive assessment of its linearity, precision, accuracy, and robustness has demonstrated its compliance with FDA standards. Integration with Nucleic Acid-Based Amplification (NASBA) has showcased its selectivity for InfA, enabling the detection of InfA RNA with a standard heater set at 41 °C. This platform offers a straightforward setup well-suited for use at low-resource facilities.