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An Outbreak of Covid-19 on an Aircraft Carrier - NEJM

Mary Wilson

Well-known member
November 11, 2020
DOI: 10.1056/NEJMoa2019375

Matthew R. Kasper, Ph.D., Jesse R. Geibe, M.D., Christine L. Sears, M.D., Asha J. Riegodedios, M.S.P.H., Tina Luse, M.P.H., Annette M. Von Thun, M.D., Michael B. McGinnis, M.D., Niels Olson, M.D., Daniel Houskamp, M.D., Robert Fenequito, M.D., Timothy H. Burgess, M.D., Adam W. Armstrong, M.D., et al.

Abstract

BACKGROUND

An outbreak of coronavirus disease 2019 (Covid-19) occurred on the U.S.S. Theodore Roosevelt, a nuclear-powered aircraft carrier with a crew of 4779 personnel.

METHODS

We obtained clinical and demographic data for all crew members, including results of testing by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). All crew members were followed up for a minimum of 10 weeks, regardless of test results or the absence of symptoms.

RESULTS

The crew was predominantly young (mean age, 27 years) and was in general good health, meeting U.S. Navy standards for sea duty. Over the course of the outbreak, 1271 crew members (26.6% of the crew) tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by rRT-PCR testing, and more than 1000 infections were identified within 5 weeks after the first laboratory-confirmed infection. An additional 60 crew members had suspected Covid-19 (i.e., illness that met Council of State and Territorial Epidemiologists clinical criteria for Covid-19 without a positive test result). Among the crew members with laboratory-confirmed infection, 76.9% (978 of 1271) had no symptoms at the time that they tested positive and 55.0% had symptoms develop at any time during the clinical course. Among the 1331 crew members with suspected or confirmed Covid-19, 23 (1.7%) were hospitalized, 4 (0.3%) received intensive care, and 1 died. Crew members who worked in confined spaces appeared more likely to become infected.
...
https://www.nejm.org/doi/full/10.1056/NEJMoa2019375
 
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