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An influenza HA Computationally Optimized Broadly Reactive Antigen elicits antibodies endowed with group-1 heterosubtypic breadth against swine influe

tetano

Editor, Senior Moderator
J Virol. 2020 Jan 29. pii: JVI.02061-19. doi: 10.1128/JVI.02061-19. [Epub ahead of print] [h=1]An influenza HA Computationally Optimized Broadly Reactive Antigen elicits antibodies endowed with group-1 heterosubtypic breadth against swine influenza viruses.[/h]
Skarlupka AL[SUP]1[/SUP], Reneer ZB[SUP]1[/SUP], Abreu RB[SUP]1[/SUP], Ross TM[SUP]1,[/SUP][SUP]2[/SUP], Sautto GA[SUP]3[/SUP].
[h=3]Author information[/h]



[h=3]Abstract[/h] Computationally Optimized Broadly Reactive Antigens (COBRA) designed for different influenza virus subtypes (H1N1, H3N2 and H5N1) elicit a subtype-specific broad antibody (Ab) response in na?ve as well as in pre-immune influenza virus animal models (1-9).….
Copyright ? 2020 American Society for Microbiology.



PMID: 31996430 DOI: 10.1128/JVI.02061-19
 
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