tetano
Editor, Senior Moderator
Am J Trop Med Hyg
. 2021 May 31;tpmd201598.
doi: 10.4269/ajtmh.20-1598. Online ahead of print.
Risk Factors for Death Among 120,804 Hospitalized Patients with Confirmed COVID-19 in São Paulo, Brazil
Patricia Vieira da Silva[SUP] 1 [/SUP], Silvano Barbosa de Oliveira[SUP] 2 3 4 [/SUP], Juan José Cortez Escalante[SUP] 2 3 [/SUP], Maria Almiron[SUP] 2 3 [/SUP], Daniel Henrique Tsuha[SUP] 1 [/SUP], Helena Keico Sato[SUP] 5 [/SUP], Paulo Rossi Menezes[SUP] 6 [/SUP], Regiane Cardoso de Paula[SUP] 6 [/SUP], Tatiana Lang D'Agostini[SUP] 6 [/SUP], Julio Croda[SUP] 1 7 [/SUP]
Affiliations
Abstract
São Paulo is a state in Brazil with one of the highest numbers of confirmed and severe cases of coronavirus disease (COVID-19), with an incidence of 294 hospitalizations per 100,000 inhabitants. We report the clinical characteristics and outcomes of 120,804 hospitalized patients with confirmed COVID-19 from February 26 to October 10, 2020, in São Paulo. Characteristics of patients who died and survived were compared using a survival analysis. The median age was 60 years (interquartile range [IQR], 47-72), 67,821 (56.1%) were men, and 61,659 (51.0%) were white. Most hospitalized patients (79,812; 66.1%) reported one or more comorbidities, 41,708 (34.5%) hospitalized patients were admitted to intensive care units, and 33,079 (27.4%) died. Men (hazard ratio
, 1.22; 95% confidence interval [CI], 1.18-1.25), elderly individuals (HR, 3.85; 95% CI, 3.68-4.02), and patients with chronic cardiovascular disease including hypertension (HR, 1.05; 95% CI, 1.02-1.08), chronic lung disease (HR, 1.38; 95% CI, 1.31-1.45), diabetes mellitus (HR, 1.14; 95% CI, 1.11-1.18), and chronic neurological disease (HR, 1.48; 95% CI, 1.41-1.55) were at higher risk for death from COVID-19.
. 2021 May 31;tpmd201598.
doi: 10.4269/ajtmh.20-1598. Online ahead of print.
Risk Factors for Death Among 120,804 Hospitalized Patients with Confirmed COVID-19 in São Paulo, Brazil
Patricia Vieira da Silva[SUP] 1 [/SUP], Silvano Barbosa de Oliveira[SUP] 2 3 4 [/SUP], Juan José Cortez Escalante[SUP] 2 3 [/SUP], Maria Almiron[SUP] 2 3 [/SUP], Daniel Henrique Tsuha[SUP] 1 [/SUP], Helena Keico Sato[SUP] 5 [/SUP], Paulo Rossi Menezes[SUP] 6 [/SUP], Regiane Cardoso de Paula[SUP] 6 [/SUP], Tatiana Lang D'Agostini[SUP] 6 [/SUP], Julio Croda[SUP] 1 7 [/SUP]
Affiliations
- PMID: 34061773
- DOI: 10.4269/ajtmh.20-1598
Abstract
São Paulo is a state in Brazil with one of the highest numbers of confirmed and severe cases of coronavirus disease (COVID-19), with an incidence of 294 hospitalizations per 100,000 inhabitants. We report the clinical characteristics and outcomes of 120,804 hospitalized patients with confirmed COVID-19 from February 26 to October 10, 2020, in São Paulo. Characteristics of patients who died and survived were compared using a survival analysis. The median age was 60 years (interquartile range [IQR], 47-72), 67,821 (56.1%) were men, and 61,659 (51.0%) were white. Most hospitalized patients (79,812; 66.1%) reported one or more comorbidities, 41,708 (34.5%) hospitalized patients were admitted to intensive care units, and 33,079 (27.4%) died. Men (hazard ratio
, 1.22; 95% confidence interval [CI], 1.18-1.25), elderly individuals (HR, 3.85; 95% CI, 3.68-4.02), and patients with chronic cardiovascular disease including hypertension (HR, 1.05; 95% CI, 1.02-1.08), chronic lung disease (HR, 1.38; 95% CI, 1.31-1.45), diabetes mellitus (HR, 1.14; 95% CI, 1.11-1.18), and chronic neurological disease (HR, 1.48; 95% CI, 1.41-1.55) were at higher risk for death from COVID-19.