tetano
Editor, Senior Moderator
Am J Trop Med Hyg. 2020 May 7. doi: 10.4269/ajtmh.20-0376. [Epub ahead of print]
Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with Novel Coronavirus Disease (COVID-19) Treated with Hydroxychloroquine.
Asli R[SUP]1[/SUP], Abdullah MS[SUP]2,[/SUP][SUP]1[/SUP], Chong PL[SUP]1[/SUP], Metussin D[SUP]1[/SUP], Momin RN[SUP]1[/SUP], Mani BI[SUP]3[/SUP], Chong VH[SUP]1,[/SUP][SUP]3,[/SUP][SUP]2[/SUP].
Author information
Abstract
Novel coronavirus disease (COVID-19) is a highly contagious disease caused by severe adult respiratory syndrome-coronavirus-2 that has resulted in the current global pandemic. Currently, there is no available treatment proven to be effective against COVID-19, but multiple medications, including hydroxychloroquine (HCQ), are used off label. We report the case of a 60-year-old woman without any cardiac history who developed right bundle brunch block and critically prolonged corrected electrocardiographic QT interval (QTc 631 ms) after treatment for 3 days with HCQ, which resolved on discontinuation of the medication. This case highlights a significant and potentially life-threatening complication of HCQ use.
PMID:32383430DOI:10.4269/ajtmh.20-0376
Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with Novel Coronavirus Disease (COVID-19) Treated with Hydroxychloroquine.
Asli R[SUP]1[/SUP], Abdullah MS[SUP]2,[/SUP][SUP]1[/SUP], Chong PL[SUP]1[/SUP], Metussin D[SUP]1[/SUP], Momin RN[SUP]1[/SUP], Mani BI[SUP]3[/SUP], Chong VH[SUP]1,[/SUP][SUP]3,[/SUP][SUP]2[/SUP].
Author information
Abstract
Novel coronavirus disease (COVID-19) is a highly contagious disease caused by severe adult respiratory syndrome-coronavirus-2 that has resulted in the current global pandemic. Currently, there is no available treatment proven to be effective against COVID-19, but multiple medications, including hydroxychloroquine (HCQ), are used off label. We report the case of a 60-year-old woman without any cardiac history who developed right bundle brunch block and critically prolonged corrected electrocardiographic QT interval (QTc 631 ms) after treatment for 3 days with HCQ, which resolved on discontinuation of the medication. This case highlights a significant and potentially life-threatening complication of HCQ use.
PMID:32383430DOI:10.4269/ajtmh.20-0376