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Am J Transplant. Immunosuppression drug-related and clinical manifestation of Coronavirus disease 2019: a therapeutical hypothesis

tetano

Editor, Senior Moderator
Am J Transplant. 2020 Apr 3. doi: 10.1111/ajt.15905. [Epub ahead of print]
Immunosuppression drug-related and clinical manifestation of Coronavirus disease 2019: a therapeutical hypothesis.


Antonio R[SUP]1[/SUP], Silvia M[SUP]2[/SUP].

Author information




Abstract

We read with interest the article of Guillen et al. [SUP]1[/SUP] . Here, the authors described the management of a kidney transplanted patient infected by SARS-CoV-2 that causes novel Coronavirus disease 2019 (COVID-19). The authors stated that immunosuppressed patients might present with atypical clinical manifestation (fever, diarrhea, fatigue) without respiratory symptoms. Also Li and colleagues [SUP]2[/SUP] reported SARS-CoV-2 infection in two solid organ transplanted patients. The two heart transplanted patients presented with variable severity of COVID-19 (one mild and another with more severe manifestations requiring a prolonged hospitalization), however, both survived the event.
This article is protected by copyright. All rights reserved.



KEYWORDS:

Calcineurin inhibito; HIV; Lung Injury; Severe acute respiratory syndrome coronavirus 2


PMID:32243698DOI:10.1111/ajt.15905
 
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