tetano
Editor, Senior Moderator
Am J Public Health
. 2023 Mar 9;e1-e8.
doi: 10.2105/AJPH.2022.307167. Online ahead of print.
Design and Implementation of a Nationwide Population-Based Longitudinal Survey of SARS-CoV-2 Infection in Spain: The ENE-COVID Study
Roberto Pastor-Barriuso[SUP] 1 [/SUP], Beatriz Pérez-Gómez[SUP] 1 [/SUP], Jesús Oteo-Iglesias[SUP] 1 [/SUP], Miguel A Hernán[SUP] 1 [/SUP], Mayte Pérez-Olmeda[SUP] 1 [/SUP], Nerea Fernández- de-Larrea[SUP] 1 [/SUP], Marta Molina[SUP] 1 [/SUP], Aurora Fernández-García[SUP] 1 [/SUP], Mariano Martín[SUP] 1 [/SUP], Israel Cruz[SUP] 1 [/SUP], José L Sanmartín[SUP] 1 [/SUP], José León-Paniagua[SUP] 1 [/SUP], Juan F Muñoz-Montalvo[SUP] 1 [/SUP], Faustino Blanco[SUP] 1 [/SUP], Raquel Yotti[SUP] 1 [/SUP], Marina Pollán[SUP] 1 [/SUP]; ENE-COVID Study Group[SUP] 1 [/SUP]
Affiliations
Abstract
Data System. The Spanish National Seroepidemiological Survey of SARS-CoV-2 (or ENE-COVID; SARS-CoV-2 [severe acute respiratory syndrome coronavirus 2] is the causative agent of COVID-19) was funded by the Spanish Ministry of Health, the Instituto de Salud Carlos III, and the Spanish National Health System. Data Collection/Processing. A stratified 2-stage probability sampling was used to select a representative cohort of the noninstitutionalized population of Spain. ENE-COVID collected longitudinal data from epidemiological questionnaires and 2 SARS-CoV-2 IgG antibody tests. From April 27 to June 22, 2020, 68 287 participants (77.0% of contacted persons) received a point-of-care test and 61 095 (68.9%) also underwent a laboratory immunoassay. A second follow-up phase was conducted between November 16 and 30, 2020. Data Analysis/Dissemination. Analyses use weights to adjust for oversampling and nonresponse and account for design effects of stratification and clustering. ENE-COVID data for research purposes will be available upon request from the official study Web page. Public Health Implications. ENE-COVID, a nationwide population-based study, allowed monitoring seroprevalence of antibodies against SARS-CoV-2 at the national and regional levels, providing accurate figures by gender, age (from babies to nonagenarians), and selected risk factors; characterizing symptomatic and asymptomatic infections; and estimating the infection fatality risk during the first pandemic wave. (Am J Public Health. Published online ahead of print March 9, 2023:e1-e8. https://doi.org/10.2105/AJPH.2022.307167).
. 2023 Mar 9;e1-e8.
doi: 10.2105/AJPH.2022.307167. Online ahead of print.
Design and Implementation of a Nationwide Population-Based Longitudinal Survey of SARS-CoV-2 Infection in Spain: The ENE-COVID Study
Roberto Pastor-Barriuso[SUP] 1 [/SUP], Beatriz Pérez-Gómez[SUP] 1 [/SUP], Jesús Oteo-Iglesias[SUP] 1 [/SUP], Miguel A Hernán[SUP] 1 [/SUP], Mayte Pérez-Olmeda[SUP] 1 [/SUP], Nerea Fernández- de-Larrea[SUP] 1 [/SUP], Marta Molina[SUP] 1 [/SUP], Aurora Fernández-García[SUP] 1 [/SUP], Mariano Martín[SUP] 1 [/SUP], Israel Cruz[SUP] 1 [/SUP], José L Sanmartín[SUP] 1 [/SUP], José León-Paniagua[SUP] 1 [/SUP], Juan F Muñoz-Montalvo[SUP] 1 [/SUP], Faustino Blanco[SUP] 1 [/SUP], Raquel Yotti[SUP] 1 [/SUP], Marina Pollán[SUP] 1 [/SUP]; ENE-COVID Study Group[SUP] 1 [/SUP]
Affiliations
- PMID: 36893375
- DOI: 10.2105/AJPH.2022.307167
Abstract
Data System. The Spanish National Seroepidemiological Survey of SARS-CoV-2 (or ENE-COVID; SARS-CoV-2 [severe acute respiratory syndrome coronavirus 2] is the causative agent of COVID-19) was funded by the Spanish Ministry of Health, the Instituto de Salud Carlos III, and the Spanish National Health System. Data Collection/Processing. A stratified 2-stage probability sampling was used to select a representative cohort of the noninstitutionalized population of Spain. ENE-COVID collected longitudinal data from epidemiological questionnaires and 2 SARS-CoV-2 IgG antibody tests. From April 27 to June 22, 2020, 68 287 participants (77.0% of contacted persons) received a point-of-care test and 61 095 (68.9%) also underwent a laboratory immunoassay. A second follow-up phase was conducted between November 16 and 30, 2020. Data Analysis/Dissemination. Analyses use weights to adjust for oversampling and nonresponse and account for design effects of stratification and clustering. ENE-COVID data for research purposes will be available upon request from the official study Web page. Public Health Implications. ENE-COVID, a nationwide population-based study, allowed monitoring seroprevalence of antibodies against SARS-CoV-2 at the national and regional levels, providing accurate figures by gender, age (from babies to nonagenarians), and selected risk factors; characterizing symptomatic and asymptomatic infections; and estimating the infection fatality risk during the first pandemic wave. (Am J Public Health. Published online ahead of print March 9, 2023:e1-e8. https://doi.org/10.2105/AJPH.2022.307167).