tetano
Editor, Senior Moderator
Am J Otolaryngol
. 2023 Dec 11;45(3):104176.
doi: 10.1016/j.amjoto.2023.104176. Online ahead of print. Comparison of the incidence of smell and taste disorders between influenza and COVID-19
Claudia I Cabrera[SUP] 1 [/SUP], Kayla Hicks[SUP] 1 [/SUP], Kenneth Rodriguez[SUP] 1 [/SUP], John A Gerka Stuyt[SUP] 1 [/SUP], Grace A McComsey[SUP] 2 [/SUP], Brian D'Anza[SUP] 3 [/SUP]
Affiliations
Objective: Smell and taste disorders among patients with COVID-19 has become increasingly reported in the literature, however the prevalence varies. Post-infectious respiratory dysfunction has also been linked to influenza. In this study, we aimed to compare the rates of smell and taste disorders between COVID-19 and Influenza in unvaccinated patients.
Study design: Retrospective cohort study.
Setting: TriNetX research network.
Methods: Two queries were made on 7/1/2023 to include Influenza without a diagnosis of COVID-19 and a COVID-19 without a diagnosis of Influenza. The queries included patients from January 1 to December 31, 2022 from 102 Healthcare Organizations. The resultant population of patients with ICD-10 codes for COVID-19 and Influenza were matched using demographic characteristics to evaluate the risk of smell disorders.
Results: The overall 3-month incidence of smell and taste disorders was 0.73 % in the COVID-19 population and 0.1 % in the influenza population. The 3-month matched risk ratios were 11.1 [95 % CI (8.8,13.8)]; p < 0.001) times higher for disorders of the smell and taste secondary to COVID-19 compared to influenza.
Conclusions: Disorders of the smell and taste are more common among patients with COVID-19 compared to patients with Influenza. Beyond smell loss, patients experience additional nasal and sinus-related rhinological symptoms, pointing to COVID-19's and influenza's wider impact on overall rhinological health. We believe that due to the transient nature of these disorders, they might go underreported.
Keywords: Anosmia; COVID; Coronavirus; Influenza; Loss of sense of smell; TriNetX.
. 2023 Dec 11;45(3):104176.
doi: 10.1016/j.amjoto.2023.104176. Online ahead of print. Comparison of the incidence of smell and taste disorders between influenza and COVID-19
Claudia I Cabrera[SUP] 1 [/SUP], Kayla Hicks[SUP] 1 [/SUP], Kenneth Rodriguez[SUP] 1 [/SUP], John A Gerka Stuyt[SUP] 1 [/SUP], Grace A McComsey[SUP] 2 [/SUP], Brian D'Anza[SUP] 3 [/SUP]
Affiliations
- PMID: 38157588
- DOI: 10.1016/j.amjoto.2023.104176
Objective: Smell and taste disorders among patients with COVID-19 has become increasingly reported in the literature, however the prevalence varies. Post-infectious respiratory dysfunction has also been linked to influenza. In this study, we aimed to compare the rates of smell and taste disorders between COVID-19 and Influenza in unvaccinated patients.
Study design: Retrospective cohort study.
Setting: TriNetX research network.
Methods: Two queries were made on 7/1/2023 to include Influenza without a diagnosis of COVID-19 and a COVID-19 without a diagnosis of Influenza. The queries included patients from January 1 to December 31, 2022 from 102 Healthcare Organizations. The resultant population of patients with ICD-10 codes for COVID-19 and Influenza were matched using demographic characteristics to evaluate the risk of smell disorders.
Results: The overall 3-month incidence of smell and taste disorders was 0.73 % in the COVID-19 population and 0.1 % in the influenza population. The 3-month matched risk ratios were 11.1 [95 % CI (8.8,13.8)]; p < 0.001) times higher for disorders of the smell and taste secondary to COVID-19 compared to influenza.
Conclusions: Disorders of the smell and taste are more common among patients with COVID-19 compared to patients with Influenza. Beyond smell loss, patients experience additional nasal and sinus-related rhinological symptoms, pointing to COVID-19's and influenza's wider impact on overall rhinological health. We believe that due to the transient nature of these disorders, they might go underreported.
Keywords: Anosmia; COVID; Coronavirus; Influenza; Loss of sense of smell; TriNetX.