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Editor, Senior Moderator
Am J Obstet Gynecol MFM. 2020 Apr 9:100118. doi: 10.1016/j.ajogmf.2020.100118. [Epub ahead of print]
COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals.
Breslin N[SUP]1[/SUP], Baptiste C[SUP]1[/SUP], Gyamfi-Bannerman C[SUP]1[/SUP], Miller R[SUP]1[/SUP], Martinez R[SUP]2[/SUP], Bernstein K[SUP]2[/SUP], Ring L[SUP]2[/SUP], Landau R[SUP]2[/SUP], Purisch S[SUP]1[/SUP], Friedman AM[SUP]1[/SUP], Fuchs K[SUP]1[/SUP], Sutton D[SUP]1[/SUP], Andrikopoulou M[SUP]1[/SUP], Rupley D[SUP]3[/SUP], Sheen JJ[SUP]1[/SUP], Aubey J[SUP]3[/SUP], Zork N[SUP]1[/SUP], Moroz L[SUP]1[/SUP], Mourad M[SUP]1[/SUP], Wapner R[SUP]1[/SUP], Simpson LL[SUP]1[/SUP], D'Alton ME[SUP]1[/SUP], Goffman D[SUP]1[/SUP].
Author information
Abstract
The novel coronavirus 2019, or COVID-19, infection has rapidly spread through the New York metropolitan area since the first reported case in the state on March 1, 2020. New York currently represents an epicenter for COVID-19 infection in the United States, with 84,735 cases reported as of April 2, 2020. We previously presented an early experience with seven COVID-positive patients in pregnancy, including two women who were diagnosed with COVID-19 following an asymptomatic initial presentation. We now describe a series of 43 test-confirmed cases of COVID-19 presenting to a pair of affiliated New York City hospitals over two weeks from March 13 to 27, 2020. Fourteen (32.6%) patients presented without any COVID-associated viral symptoms, and were identified either after developing symptoms during admission or following the implementation of universal testing for all obstetrical admissions on March 22. Of these, 10/14 (71.4%) developed symptoms or signs of COVID-19 infection over the course of their delivery admission or early after postpartum discharge. Of the other 29 (67.4%) patients who presented with symptomatic COVID-19 infection, three women ultimately required antenatal admission for viral symptoms, and an additional patient represented six days postpartum after a successful labor induction with worsening respiratory status that required oxygen supplementation. There were no confirmed cases of COVID-19 detected in neonates upon initial testing on the first day of life. Applying COVID-19 disease severity characteristics as described by Wu et al, 37 (86%) women possessed mild disease, four (9.3%) exhibited severe disease, and two (4.7%) developed critical disease; these percentages are similar to those described for non-pregnant adults with COVID-19 infections (about 80% mild, 15% severe, and 5% critical disease).
? 2020 Elsevier Inc. All rights reserved.
KEYWORDS:
COVID-19; novel coronavirus; pregnancy
PMID:32292903PMCID:PMC7144599DOI:10.1016/j.ajogmf.2020.100118
Free PMC Article
COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals.
Breslin N[SUP]1[/SUP], Baptiste C[SUP]1[/SUP], Gyamfi-Bannerman C[SUP]1[/SUP], Miller R[SUP]1[/SUP], Martinez R[SUP]2[/SUP], Bernstein K[SUP]2[/SUP], Ring L[SUP]2[/SUP], Landau R[SUP]2[/SUP], Purisch S[SUP]1[/SUP], Friedman AM[SUP]1[/SUP], Fuchs K[SUP]1[/SUP], Sutton D[SUP]1[/SUP], Andrikopoulou M[SUP]1[/SUP], Rupley D[SUP]3[/SUP], Sheen JJ[SUP]1[/SUP], Aubey J[SUP]3[/SUP], Zork N[SUP]1[/SUP], Moroz L[SUP]1[/SUP], Mourad M[SUP]1[/SUP], Wapner R[SUP]1[/SUP], Simpson LL[SUP]1[/SUP], D'Alton ME[SUP]1[/SUP], Goffman D[SUP]1[/SUP].
Author information
Abstract
The novel coronavirus 2019, or COVID-19, infection has rapidly spread through the New York metropolitan area since the first reported case in the state on March 1, 2020. New York currently represents an epicenter for COVID-19 infection in the United States, with 84,735 cases reported as of April 2, 2020. We previously presented an early experience with seven COVID-positive patients in pregnancy, including two women who were diagnosed with COVID-19 following an asymptomatic initial presentation. We now describe a series of 43 test-confirmed cases of COVID-19 presenting to a pair of affiliated New York City hospitals over two weeks from March 13 to 27, 2020. Fourteen (32.6%) patients presented without any COVID-associated viral symptoms, and were identified either after developing symptoms during admission or following the implementation of universal testing for all obstetrical admissions on March 22. Of these, 10/14 (71.4%) developed symptoms or signs of COVID-19 infection over the course of their delivery admission or early after postpartum discharge. Of the other 29 (67.4%) patients who presented with symptomatic COVID-19 infection, three women ultimately required antenatal admission for viral symptoms, and an additional patient represented six days postpartum after a successful labor induction with worsening respiratory status that required oxygen supplementation. There were no confirmed cases of COVID-19 detected in neonates upon initial testing on the first day of life. Applying COVID-19 disease severity characteristics as described by Wu et al, 37 (86%) women possessed mild disease, four (9.3%) exhibited severe disease, and two (4.7%) developed critical disease; these percentages are similar to those described for non-pregnant adults with COVID-19 infections (about 80% mild, 15% severe, and 5% critical disease).
? 2020 Elsevier Inc. All rights reserved.
KEYWORDS:
COVID-19; novel coronavirus; pregnancy
PMID:32292903PMCID:PMC7144599DOI:10.1016/j.ajogmf.2020.100118
Free PMC Article