tetano
Editor, Senior Moderator
Am J Med Open
. 2021;1:100003.
doi: 10.1016/j.ajmo.2021.100003. Epub 2021 Nov 22.
Outcomes in patients hospitalized for COVID-19 among Asian, Pacific Islander, and Hispanic subgroups in the American Heart Association COVID-19 registry
Nilay S Shah[SUP] 1 2 [/SUP], Gina M Giase[SUP] 1 [/SUP], Lucia C Petito[SUP] 1 [/SUP], Namratha R Kandula[SUP] 1 3 [/SUP], Fatima Rodriguez[SUP] 4 [/SUP], Jeffrey J Hsu[SUP] 5 [/SUP], Daniel R Wang[SUP] 5 [/SUP], Sadiya S Khan[SUP] 1 2 [/SUP]
Affiliations
Abstract
Background: Coronavirus disease 2019 (COVID-19) data from race/ethnic subgroups remain limited, potentially masking subgroup-level heterogeneity. We evaluated differences in outcomes in Asian American/Pacific Islander (AAPI) and Hispanic/Latino subgroups compared with non-Hispanic White patients hospitalized with COVID-19.
Methods: In the American Heart Association COVID-19 registry including 105 US hospitals, mortality and major adverse cardiovascular events in adults age ≥18 years hospitalized with COVID-19 between March-November 2020 were evaluated. Race/ethnicity groups included AAPI overall and subgroups (Chinese, Asian Indian, Vietnamese, and Pacific Islander), Hispanic/Latino overall and subgroups (Mexican, Puerto Rican), compared with non-Hispanic White (NHW).
Results: Among 13,511 patients, 7% were identified as AAPI (of whom 17% were identified as Chinese, 9% Asian Indian, 8% Pacific Islander, and 7% Vietnamese); 35% as Hispanic (of whom 15% were identified as Mexican and 1% Puerto Rican); and 59% as NHW. Mean [SD] age at hospitalization was lower in Asian Indian (60.4 [17.4] years), Pacific Islander (49.4 [16.7] years), and Mexican patients (57.4 [16.9] years), compared with NHW patients (66.9 [17.3] years, p<0.01). Mean age at death was lower in Mexican (67.7 [15.5] years) compared with NHW patients (75.5 [13.5] years, p<0.01). No differences in odds of mortality or MACE in AAPI or Hispanic patients relative to NHW patients were observed after adjustment for age.
Conclusions: Pacific Islander, Asian Indian, and Mexican patients hospitalized with COVID-19 in the AHA registry were significantly younger than NHW patients. COVID-19 infection leading to hospitalization may disproportionately burden some younger AAPI and Hispanic subgroups in the US.
Keywords: Asian; COVID-19; Hispanic; Pacific Islander; disparities.
. 2021;1:100003.
doi: 10.1016/j.ajmo.2021.100003. Epub 2021 Nov 22.
Outcomes in patients hospitalized for COVID-19 among Asian, Pacific Islander, and Hispanic subgroups in the American Heart Association COVID-19 registry
Nilay S Shah[SUP] 1 2 [/SUP], Gina M Giase[SUP] 1 [/SUP], Lucia C Petito[SUP] 1 [/SUP], Namratha R Kandula[SUP] 1 3 [/SUP], Fatima Rodriguez[SUP] 4 [/SUP], Jeffrey J Hsu[SUP] 5 [/SUP], Daniel R Wang[SUP] 5 [/SUP], Sadiya S Khan[SUP] 1 2 [/SUP]
Affiliations
- PMID: 34918003
- PMCID: PMC8606255
- DOI: 10.1016/j.ajmo.2021.100003
Abstract
Background: Coronavirus disease 2019 (COVID-19) data from race/ethnic subgroups remain limited, potentially masking subgroup-level heterogeneity. We evaluated differences in outcomes in Asian American/Pacific Islander (AAPI) and Hispanic/Latino subgroups compared with non-Hispanic White patients hospitalized with COVID-19.
Methods: In the American Heart Association COVID-19 registry including 105 US hospitals, mortality and major adverse cardiovascular events in adults age ≥18 years hospitalized with COVID-19 between March-November 2020 were evaluated. Race/ethnicity groups included AAPI overall and subgroups (Chinese, Asian Indian, Vietnamese, and Pacific Islander), Hispanic/Latino overall and subgroups (Mexican, Puerto Rican), compared with non-Hispanic White (NHW).
Results: Among 13,511 patients, 7% were identified as AAPI (of whom 17% were identified as Chinese, 9% Asian Indian, 8% Pacific Islander, and 7% Vietnamese); 35% as Hispanic (of whom 15% were identified as Mexican and 1% Puerto Rican); and 59% as NHW. Mean [SD] age at hospitalization was lower in Asian Indian (60.4 [17.4] years), Pacific Islander (49.4 [16.7] years), and Mexican patients (57.4 [16.9] years), compared with NHW patients (66.9 [17.3] years, p<0.01). Mean age at death was lower in Mexican (67.7 [15.5] years) compared with NHW patients (75.5 [13.5] years, p<0.01). No differences in odds of mortality or MACE in AAPI or Hispanic patients relative to NHW patients were observed after adjustment for age.
Conclusions: Pacific Islander, Asian Indian, and Mexican patients hospitalized with COVID-19 in the AHA registry were significantly younger than NHW patients. COVID-19 infection leading to hospitalization may disproportionately burden some younger AAPI and Hispanic subgroups in the US.
Keywords: Asian; COVID-19; Hispanic; Pacific Islander; disparities.
