tetano
Editor, Senior Moderator
Am J Infect Control
. 2022 Sep 15;S0196-6553(22)00675-7.
doi: 10.1016/j.ajic.2022.09.007. Online ahead of print.
High mortality and morbidity among vaccinated residents infected with the SARS-CoV-2 Omicron variant during an outbreak in a nursing home in Kyoto City, Japan
Yasufumi Matsumura[SUP] 1 [/SUP], Masaki Yamamoto[SUP] 2 [/SUP], Koh Shinohara[SUP] 2 [/SUP], Yasuhiro Tsuchido[SUP] 2 [/SUP], Satomi Yukawa[SUP] 2 [/SUP], Taro Noguchi[SUP] 2 [/SUP], Takeshi Ikeda[SUP] 3 [/SUP], Miki Nagao[SUP] 2 [/SUP]
Affiliations
Abstract
Background: Outbreaks of coronavirus disease 2019 (COVID-19) in long-term care facilities are difficult to control and are associated with mortality, although vaccination have contributed to improvements. This study reports clinical impacts of a COVID-19 outbreak in a nursing home for elderly individuals in Kyoto City, Japan.
Methods: We performed epidemiologic and molecular investigations of the outbreak and characterized outcomes of the nursing home residents.
Results: During the outbreak period, a total of 31 residents (39.2%) and 26 staff members (49.1%) were infected with COVID-19. All residents and staff received two doses of a vaccine approximately 7 months prior. Only four residents were admitted to hospitals, and 10 residents with severe hypoxemia could not be transferred to a hospital due to a shortage of beds for COVID-19 patients. Within 90 days of the onset of the outbreak, 8 residents with COVID-19 (25.8%) and 3 uninfected residents (6.2%) died. A total of 48.4% of residents with COVID-19 and 8.3% of uninfected residents developed one or more comorbidities. Viral genome analysis showed that the outbreak was caused by the Omicron BA.1.1.2 variant.
Conclusions: Despite vaccination, high mortality and morbidity were observed in the COVID-19 outbreak due to the Omicron variant. Limiting medical care for residents with COVID-19 in facilities that experience ongoing outbreaks may be needed to reduce the risk of mortality among nursing home residents.
Keywords: COVID-19; SARS-CoV-2; nursing home; outbreak; viral genome.
. 2022 Sep 15;S0196-6553(22)00675-7.
doi: 10.1016/j.ajic.2022.09.007. Online ahead of print.
High mortality and morbidity among vaccinated residents infected with the SARS-CoV-2 Omicron variant during an outbreak in a nursing home in Kyoto City, Japan
Yasufumi Matsumura[SUP] 1 [/SUP], Masaki Yamamoto[SUP] 2 [/SUP], Koh Shinohara[SUP] 2 [/SUP], Yasuhiro Tsuchido[SUP] 2 [/SUP], Satomi Yukawa[SUP] 2 [/SUP], Taro Noguchi[SUP] 2 [/SUP], Takeshi Ikeda[SUP] 3 [/SUP], Miki Nagao[SUP] 2 [/SUP]
Affiliations
- PMID: 36116676
- DOI: 10.1016/j.ajic.2022.09.007
Abstract
Background: Outbreaks of coronavirus disease 2019 (COVID-19) in long-term care facilities are difficult to control and are associated with mortality, although vaccination have contributed to improvements. This study reports clinical impacts of a COVID-19 outbreak in a nursing home for elderly individuals in Kyoto City, Japan.
Methods: We performed epidemiologic and molecular investigations of the outbreak and characterized outcomes of the nursing home residents.
Results: During the outbreak period, a total of 31 residents (39.2%) and 26 staff members (49.1%) were infected with COVID-19. All residents and staff received two doses of a vaccine approximately 7 months prior. Only four residents were admitted to hospitals, and 10 residents with severe hypoxemia could not be transferred to a hospital due to a shortage of beds for COVID-19 patients. Within 90 days of the onset of the outbreak, 8 residents with COVID-19 (25.8%) and 3 uninfected residents (6.2%) died. A total of 48.4% of residents with COVID-19 and 8.3% of uninfected residents developed one or more comorbidities. Viral genome analysis showed that the outbreak was caused by the Omicron BA.1.1.2 variant.
Conclusions: Despite vaccination, high mortality and morbidity were observed in the COVID-19 outbreak due to the Omicron variant. Limiting medical care for residents with COVID-19 in facilities that experience ongoing outbreaks may be needed to reduce the risk of mortality among nursing home residents.
Keywords: COVID-19; SARS-CoV-2; nursing home; outbreak; viral genome.