tetano
Editor, Senior Moderator
Allergol Immunopathol (Madr)
. 2021 Jan 2;49(1):113-117.
doi: 10.15586/aei.v49i1.40. eCollection 2021.
Inhaled corticosteroids may have a protective effect against coronavirus infection
Alicia Armentia[SUP] 1 [/SUP], Sara Fern?ndez Cort?s[SUP] 2 [/SUP], Angela Moro Sim?n[SUP] 2 [/SUP], Blanca Mart?n-Armentia[SUP] 2 [/SUP], Sara Mart?n-Armentia[SUP] 3 [/SUP], Daniel Ramos Pollo[SUP] 4 [/SUP], Juan Claudio Navarro Ca?adas[SUP] 4 [/SUP], Javier Visa Ca?o[SUP] 4 [/SUP], ?lvaro Sanz Rubiales[SUP] 5 [/SUP], Joaqu?n Rodriguez Fra[SUP] 5 [/SUP], Sara Garc?a Vaquero[SUP] 6 [/SUP], Marta Cano Pazos[SUP] 6 [/SUP], Jes?s Gal?n de la Calle[SUP] 6 [/SUP], Edgardo Raul Lowell[SUP] 6 [/SUP], Cristina Crespo Soto[SUP] 7 [/SUP], Carmen S?nchez Toledano[SUP] 8 [/SUP], Aurora Sacrist?n Salgado[SUP] 9 [/SUP]
Affiliations
Abstract
Background: Spain has been severely affected by the COVID-19 epidemic, with 195,944 persons infected and 20,453 deaths at the time of writing. Older people with respiratory or cardiac conditions are most at risk.
Objective: The aim was to compare respiratory symptoms in nursing home residents and patients with uncontrolled asthma, who are considered vulnerable to COVID-19.
Methods: We studied 134 nursing home residents and 139 patients with uncontrolled asthma, groups vulnerable to COVID-19. Demographic characteristics, clinical manifestations, outcomes, key laboratory results, and radiological images were collected from medical records. COVID-19 infection was detected by polymerase chain reaction (PCR).
Results: Thirteen (9.3%) patients with uncontrolled asthma, all receiving inhaled corticosteroids were infected by COVID-19. Eighty (60%) nursing home residents were infected; only 28, all of whom had received inhaled corticosteroids, had a good prognosis.
Conclusions: Early treatment with inhaled corticosteroids may be helpful in COVID-19 infection. Persons with an allergy might have some protective mechanisms against coronavirus.
Keywords: COVID; Th2 cell immunity; allergy; asthma severe; coronavirus; coronavirus infection; corticosteroids; nursing home; telemedicine.
. 2021 Jan 2;49(1):113-117.
doi: 10.15586/aei.v49i1.40. eCollection 2021.
Inhaled corticosteroids may have a protective effect against coronavirus infection
Alicia Armentia[SUP] 1 [/SUP], Sara Fern?ndez Cort?s[SUP] 2 [/SUP], Angela Moro Sim?n[SUP] 2 [/SUP], Blanca Mart?n-Armentia[SUP] 2 [/SUP], Sara Mart?n-Armentia[SUP] 3 [/SUP], Daniel Ramos Pollo[SUP] 4 [/SUP], Juan Claudio Navarro Ca?adas[SUP] 4 [/SUP], Javier Visa Ca?o[SUP] 4 [/SUP], ?lvaro Sanz Rubiales[SUP] 5 [/SUP], Joaqu?n Rodriguez Fra[SUP] 5 [/SUP], Sara Garc?a Vaquero[SUP] 6 [/SUP], Marta Cano Pazos[SUP] 6 [/SUP], Jes?s Gal?n de la Calle[SUP] 6 [/SUP], Edgardo Raul Lowell[SUP] 6 [/SUP], Cristina Crespo Soto[SUP] 7 [/SUP], Carmen S?nchez Toledano[SUP] 8 [/SUP], Aurora Sacrist?n Salgado[SUP] 9 [/SUP]
Affiliations
- PMID: 33528938
- DOI: 10.15586/aei.v49i1.40
Abstract
Background: Spain has been severely affected by the COVID-19 epidemic, with 195,944 persons infected and 20,453 deaths at the time of writing. Older people with respiratory or cardiac conditions are most at risk.
Objective: The aim was to compare respiratory symptoms in nursing home residents and patients with uncontrolled asthma, who are considered vulnerable to COVID-19.
Methods: We studied 134 nursing home residents and 139 patients with uncontrolled asthma, groups vulnerable to COVID-19. Demographic characteristics, clinical manifestations, outcomes, key laboratory results, and radiological images were collected from medical records. COVID-19 infection was detected by polymerase chain reaction (PCR).
Results: Thirteen (9.3%) patients with uncontrolled asthma, all receiving inhaled corticosteroids were infected by COVID-19. Eighty (60%) nursing home residents were infected; only 28, all of whom had received inhaled corticosteroids, had a good prognosis.
Conclusions: Early treatment with inhaled corticosteroids may be helpful in COVID-19 infection. Persons with an allergy might have some protective mechanisms against coronavirus.
Keywords: COVID; Th2 cell immunity; allergy; asthma severe; coronavirus; coronavirus infection; corticosteroids; nursing home; telemedicine.