Mary Wilson
Well-known member
In order to provide our readers with timely access to new content, papers accepted by the American Journal of Tropical Medicine and Hygiene are posted online ahead of print publication.Papers that have been accepted for publication are peer-reviewed and copy edited but do not incorporate all corrections or constitute the nal versions that will appear in the Journal. Final,corrected papers will be published online concurrent with the release of the print issue.
Received: 23 Jun 2021 | Accepted: 20 Jan 2022 | Published Online: 25 Feb 2022
DOI:https://doi.org/10.4269/ajtmh.21-0713
Mory Keita,1,2* Mahamoud Sama Cherif,3 Billy Sivahera,4 Samuel T. Boland,5 Freddy Banza-Mutoka,1 Mamadou Kourouma,4Alseny Modet Camara,6 Youssouf Sidibe,7 Jean Paul Kimenyi,1 Lamine Diassy,4 Angelo Loua,8 Ibrahima Sory Fofana,4Youba Kandako,4 Dobo Onivogui,9 Enogo Koivogui,10 Tamba Jacques Millimono,10 Fode Diakite,4 Mamadou Balde,4Bienvenu Houndjo,4 Ngoy Nsenga,1 Ambrose Talisuna,1 Alexandre Delamou,3,11 Olivia Keiser,2 Georges Alfred Ki-Zerbo,4and Abdou Salam Gueye1
Abstract
In this case report, we describe a clinical presentation and therapeutic history of a unique case diagnosed with Lassa fever and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 23-year-old man from Yomou prefecture in southeast Guinea identified with suspected Ebola Virus Disease (EVD) in the midst of an ongoing outbreak of that disease in the same region. On May 3, 2021, he was admitted to the NzerekoreEpidemic disease treatment cen- ter where his clinical condition deteriorated significantly. Laboratory testing performed on the same day reveals a nega- tive EVD polymerase chain reaction (PCR). Three days later, the patient was tested positive for SARS-CoV-2 and Lassa fever by reverse transcriptase PCR (RT-PCR) assays. Laboratory examination also indicated severe hematological and biochemical deteriorations in the patient. This case substantiates the need for systematic differential diagnosis during epidemic-prone disease outbreaks to better manage severely unwell patients.
(NOTE: You will have to Download PDF to view)
https://www.ajtmh.org/view/journals...tmh.21-0713/article-10.4269-ajtmh.21-0713.xml
Received: 23 Jun 2021 | Accepted: 20 Jan 2022 | Published Online: 25 Feb 2022
DOI:https://doi.org/10.4269/ajtmh.21-0713
Mory Keita,1,2* Mahamoud Sama Cherif,3 Billy Sivahera,4 Samuel T. Boland,5 Freddy Banza-Mutoka,1 Mamadou Kourouma,4Alseny Modet Camara,6 Youssouf Sidibe,7 Jean Paul Kimenyi,1 Lamine Diassy,4 Angelo Loua,8 Ibrahima Sory Fofana,4Youba Kandako,4 Dobo Onivogui,9 Enogo Koivogui,10 Tamba Jacques Millimono,10 Fode Diakite,4 Mamadou Balde,4Bienvenu Houndjo,4 Ngoy Nsenga,1 Ambrose Talisuna,1 Alexandre Delamou,3,11 Olivia Keiser,2 Georges Alfred Ki-Zerbo,4and Abdou Salam Gueye1
Abstract
In this case report, we describe a clinical presentation and therapeutic history of a unique case diagnosed with Lassa fever and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 23-year-old man from Yomou prefecture in southeast Guinea identified with suspected Ebola Virus Disease (EVD) in the midst of an ongoing outbreak of that disease in the same region. On May 3, 2021, he was admitted to the NzerekoreEpidemic disease treatment cen- ter where his clinical condition deteriorated significantly. Laboratory testing performed on the same day reveals a nega- tive EVD polymerase chain reaction (PCR). Three days later, the patient was tested positive for SARS-CoV-2 and Lassa fever by reverse transcriptase PCR (RT-PCR) assays. Laboratory examination also indicated severe hematological and biochemical deteriorations in the patient. This case substantiates the need for systematic differential diagnosis during epidemic-prone disease outbreaks to better manage severely unwell patients.
(NOTE: You will have to Download PDF to view)
https://www.ajtmh.org/view/journals...tmh.21-0713/article-10.4269-ajtmh.21-0713.xml
