tetano
Editor, Senior Moderator
Aging (Albany NY). 2020 Apr 10;12. doi: 10.18632/aging.102999. [Epub ahead of print]
Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients.
Yang Z[SUP]1[/SUP], Shi J[SUP]1[/SUP], He Z[SUP]2[/SUP], L? Y[SUP]1[/SUP], Xu Q[SUP]1[/SUP], Ye C[SUP]1[/SUP], Chen S[SUP]1[/SUP], Tang B[SUP]1[/SUP], Yin K[SUP]1[/SUP], Lu Y[SUP]1[/SUP], Chen X[SUP]1[/SUP].
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Abstract
OBJECTIVE:
This study aimed to investigate the potential parameters associated with imaging progression on chest CT from coronavirus disease 19 (COVID-19) patients.
RESULTS:
The average age of 273 COVID-19 patients enrolled with imaging progression were older than those without imaging progression (p = 0.006). The white blood cells, platelets, neutrophils and acid glycoprotein were all decreased in imaging progression patients (all p < 0.05), and monocytes were increased (p = 0.025). The parameters including homocysteine, urea, creatinine and serum cystatin C were significantly higher in imaging progression patients (all p < 0.05), while eGFR decreased (p < 0.001). Monocyte-lymphocyte ratio (MLR) was significantly higher in imaging progression patients compared to that in imaging progression-free ones (p < 0.001). Logistic models revealed that age, MLR, homocysteine and period from onset to admission were factors for predicting imaging progression on chest CT at first week from COVID-19 patients (all p < 0.05).
CONCLUSION:
Age, MLR, homocysteine and period from onset to admission could predict imaging progression on chest CT from COVID-19 patients.
METHODS:
The primary outcome was imaging progression on chest CT. Baseline parameters were collected at the first day of admission. Imaging manifestations on chest CT were followed-up at (6?1) days.
KEYWORDS:
COVID-19; MLR; age; coronavirus disease 2019; monocyte-lymphocyte ratio
PMID:32275643DOI:10.18632/aging.102999
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Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients.
Yang Z[SUP]1[/SUP], Shi J[SUP]1[/SUP], He Z[SUP]2[/SUP], L? Y[SUP]1[/SUP], Xu Q[SUP]1[/SUP], Ye C[SUP]1[/SUP], Chen S[SUP]1[/SUP], Tang B[SUP]1[/SUP], Yin K[SUP]1[/SUP], Lu Y[SUP]1[/SUP], Chen X[SUP]1[/SUP].
Author information
Abstract
OBJECTIVE:
This study aimed to investigate the potential parameters associated with imaging progression on chest CT from coronavirus disease 19 (COVID-19) patients.
RESULTS:
The average age of 273 COVID-19 patients enrolled with imaging progression were older than those without imaging progression (p = 0.006). The white blood cells, platelets, neutrophils and acid glycoprotein were all decreased in imaging progression patients (all p < 0.05), and monocytes were increased (p = 0.025). The parameters including homocysteine, urea, creatinine and serum cystatin C were significantly higher in imaging progression patients (all p < 0.05), while eGFR decreased (p < 0.001). Monocyte-lymphocyte ratio (MLR) was significantly higher in imaging progression patients compared to that in imaging progression-free ones (p < 0.001). Logistic models revealed that age, MLR, homocysteine and period from onset to admission were factors for predicting imaging progression on chest CT at first week from COVID-19 patients (all p < 0.05).
CONCLUSION:
Age, MLR, homocysteine and period from onset to admission could predict imaging progression on chest CT from COVID-19 patients.
METHODS:
The primary outcome was imaging progression on chest CT. Baseline parameters were collected at the first day of admission. Imaging manifestations on chest CT were followed-up at (6?1) days.
KEYWORDS:
COVID-19; MLR; age; coronavirus disease 2019; monocyte-lymphocyte ratio
PMID:32275643DOI:10.18632/aging.102999
Free full text