tetano
Editor, Senior Moderator
Ageing Res Rev
. 2022 Dec 11;84:101818.
doi: 10.1016/j.arr.2022.101818. Online ahead of print.
Immunosenescence and inflamm-ageing in COVID-19
Mohammad Reza Zinatizadeh[SUP] 1 [/SUP], Peyman Kheirandish Zarandi[SUP] 1 [/SUP], Mohsen Ghiasi[SUP] 2 [/SUP], Hamid Kooshki[SUP] 3 [/SUP], Mozafar Mohammadi[SUP] 4 [/SUP], Jafar Amani[SUP] 5 [/SUP], Nima Rezaei[SUP] 6 [/SUP]
Affiliations
Abstract
The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people with cardiovascular disease have been proven. New findings shed light on the role of aging pathways on life span and health age. New therapies that focus on aging-related pathways may positively impact the treatment of this acute respiratory infection. Using new therapies that boost the level of the immune system can support the elderly with co-morbidities against the acute form of COVID-19. This article discusses the effect of the aging immune system against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the pathways affecting this severity of infection.
Keywords: COVID-19; Immunosenescence; Inflamm-ageing; SARS-CoV-2.
. 2022 Dec 11;84:101818.
doi: 10.1016/j.arr.2022.101818. Online ahead of print.
Immunosenescence and inflamm-ageing in COVID-19
Mohammad Reza Zinatizadeh[SUP] 1 [/SUP], Peyman Kheirandish Zarandi[SUP] 1 [/SUP], Mohsen Ghiasi[SUP] 2 [/SUP], Hamid Kooshki[SUP] 3 [/SUP], Mozafar Mohammadi[SUP] 4 [/SUP], Jafar Amani[SUP] 5 [/SUP], Nima Rezaei[SUP] 6 [/SUP]
Affiliations
- PMID: 36516928
- DOI: 10.1016/j.arr.2022.101818
Abstract
The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people with cardiovascular disease have been proven. New findings shed light on the role of aging pathways on life span and health age. New therapies that focus on aging-related pathways may positively impact the treatment of this acute respiratory infection. Using new therapies that boost the level of the immune system can support the elderly with co-morbidities against the acute form of COVID-19. This article discusses the effect of the aging immune system against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the pathways affecting this severity of infection.
Keywords: COVID-19; Immunosenescence; Inflamm-ageing; SARS-CoV-2.