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Age and Sex Differences in Rates of Influenza-Associated Hospitalizations in Hong Kong

tetano

Editor, Senior Moderator
Am J Epidemiol. 2015 Jul 27. pii: kwv068. [Epub ahead of print]
[h=1]Age and Sex Differences in Rates of Influenza-Associated Hospitalizations in Hong Kong.[/h] Wang XL, Yang L, Chan KH, Chan KP, Cao PH, Lau EH, Peiris JS, Wong CM.
[h=3]Abstract[/h] Few studies have explored age and sex differences in the disease burden of influenza, although men and women probably differ in their susceptibility to influenza infections. In this study, quasi-Poisson regression models were applied to weekly age- and sex-specific hospitalization numbers of pneumonia and influenza cases in the Hong Kong SAR, People's Republic of China, from 2004 to 2010. Age and sex differences were assessed by age- and sex-specific rates of excess hospitalization for influenza A subtypes A(H1N1), A(H3N2), and A(H1N1)pdm09 and influenza B, respectively. We found that, in children younger than 18 years, boys had a higher excess hospitalization rate than girls, with the male-to-female ratio of excess rate (MFR) ranging from 1.1 to 2.4. MFRs of hospitalization associated with different types/subtypes were less than 1.0 for adults younger than 40 years except for A(H3N2) (MFR = 1.6), while all the MFRs were equal to or higher than 1.0 in adults aged 40 years or more except for A(H1N1)pdm09 in elderly persons aged 65 years or more (MFR = 0.9). No MFR was found to be statistically significant (P < 0.05) for hospitalizations associated with influenza type/subtype. There is some limited evidence on age and sex differences in hospitalization associated with influenza in the subtropical city of Hong Kong.
? The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.


[h=4]KEYWORDS:[/h] age distribution; hospitalization; influenza; risk assessment; sex

PMID: 26219977 [PubMed - as supplied by publisher]
 
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