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Aerosol-Assisted Plasma Deposition of Hydrophobic Polycations Makes Surfaces Highly Antimicrobial

tetano

Editor, Senior Moderator
Appl Biochem Biotechnol. 2013 Oct 26. [Epub ahead of print]
Aerosol-Assisted Plasma Deposition of Hydrophobic Polycations Makes Surfaces Highly Antimicrobial.
Liu H, Kim Y, Mello K, Lovaasen J, Shah A, Rice N, Yim JH, Pappas D, Klibanov AM.
Source

Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
Abstract

The currently used multistep chemical synthesis for making surfaces antimicrobial by attaching to them hydrophobic polycations is replaced herein by an aerosol-assisted plasma deposition procedure. To this end, N,N-hexyl,methyl-PEI (HMPEI) is directly plasma-coated onto a glass surface. The resultant immobilized HMPEI coating has been thoroughly characterized and shown to be robust, bactericidal against Escherichia coli, and virucidal against human influenza virus.

PMID:
24158590
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24158590
 
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