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Advanced Healthcare Materials: Peptide Amphiphile Nanoparticles Enhance the Immune Response Against a CpG-Adjuvanted Influenza Antigen

tetano

Editor, Senior Moderator
Peptide Amphiphile Nanoparticles Enhance the Immune Response Against a CpG-Adjuvanted Influenza Antigen

Harshal Zope1,
Christophe Barnier Quer2,
Paul H. H. Bomans3,
Nico A. J. M. Sommerdijk3,
Alexander Kros1,*,
Wim Jiskoot2,*

Article first published online: 27 AUG 2013

DOI: 10.1002/adhm.201300247

? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim


Cationic peptide amphiphile nanoparticles are employed for co-delivery of immune modulator CpG and antigen. This results in better targeting to the antigen presenting cells and eliciting strong Th1 response, which is effective against the intracellular pathogens.

http://onlinelibrary.wiley.com/doi/...sCustomisedMessage=&userIsAuthenticated=false
 
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