tetano
Editor, Senior Moderator
The Journal of Infectious Diseases 2010;202:881?888
? 2010 by the Infectious Diseases Society of America. All rights reserved.
0022-1899/2010/20206-0010$15.00
DOI: 10.1086/655904
MAJOR ARTICLE
Adult Hospitalizations for Laboratory‐Positive Influenza during the 2005?2006 through 2007?2008 Seasons in the United States
Christine N. Dao,1
Laurie Kamimoto,1
Mackenzie Nowell,1
Arthur Reingold,5
Ken Gershman,6
James Meek,7
Kathryn E. Arnold,2
Monica Farley,3,4
Patricia Ryan,8
Ruth Lynfield,9
Craig Morin,9
Joan Baumbach,10
Emily Hancock,10
Shelley Zansky,11
Nancy M. Bennett,12
Ann Thomas,13
Meredith Vandermeer,13
David L. Kirschke,14
William Schaffner,15 and
Lyn Finelli;1
for the Emerging Infections Program Network
1Influenza Division, Centers for Disease Control and Prevention, 2Georgia Division of Public Health, 3Emory University School of Medicine, and 4Atlanta Veterans Administration Medical Center, Atlanta, Georgia; 5California Emerging Infections Program, Oakland, California; 6Colorado Department of Public Health, Denver, Colorado; 7Connecticut Emerging Infections Program, Yale University, New Haven, Connecticut; 8Maryland Department of Health and Mental Hygiene, Baltimore, Maryland; 9Minnesota Department of Health, St Paul, Minnesota; 10New Mexico Emerging Infections Program, Santa Fe, New Mexico; 11New York State Health Department, Albany, and 12Monroe County Health Department, Rochester, New York; 13Oregon Public Health Division, Portland, Oregon; and 14Tennessee Department of Health and 15Department of Preventive Medicine, Vanderbilt University, Nashville, Tennessee
Background.Rates of influenza‐associated hospitalizations in the United States have been estimated using modeling techniques with data from pneumonia and influenza hospitalization discharge diagnoses, but they have not been directly estimated from laboratory‐positive cases.
Methods.We calculated overall, age‐specific, and site‐specific rates of laboratory‐positive, influenza‐associated hospitalization among adults and compared demographic and clinical characteristics and outcomes of hospitalized cases by season with use of data collected by the Emerging Infections Program Network during the 2005?2006 through 2007?2008 influenza seasons.
Results.Overall rates of adult influenza‐associated hospitalization per 100,000 persons were 9.9 during the 2005?2006 season, 4.8 during the 2006?2007 season, and 18.7 during the 2007?2008 season. Rates of hospitalization varied by Emerging Infections Program site and increased with increasing age. Higher overall and age‐specific rates of hospitalization were observed during influenza A (H3) predominant seasons and during periods of increased circulation of influenza B. More than 80% of hospitalized persons each season had 1 underlying medical condition, including chronic cardiovascular and metabolic diseases.
Conclusions.Rates varied by season, age, geographic location, and type/subtype of circulating influenza viruses. Influenza‐associated hospitalization surveillance is essential for assessing the relative severity of influenza seasons over time and the burden of influenza‐associated complications.
http://www.journals.uchicago.edu/doi/abs/10.1086/655904
? 2010 by the Infectious Diseases Society of America. All rights reserved.
0022-1899/2010/20206-0010$15.00
DOI: 10.1086/655904
MAJOR ARTICLE
Adult Hospitalizations for Laboratory‐Positive Influenza during the 2005?2006 through 2007?2008 Seasons in the United States
Christine N. Dao,1
Laurie Kamimoto,1
Mackenzie Nowell,1
Arthur Reingold,5
Ken Gershman,6
James Meek,7
Kathryn E. Arnold,2
Monica Farley,3,4
Patricia Ryan,8
Ruth Lynfield,9
Craig Morin,9
Joan Baumbach,10
Emily Hancock,10
Shelley Zansky,11
Nancy M. Bennett,12
Ann Thomas,13
Meredith Vandermeer,13
David L. Kirschke,14
William Schaffner,15 and
Lyn Finelli;1
for the Emerging Infections Program Network
1Influenza Division, Centers for Disease Control and Prevention, 2Georgia Division of Public Health, 3Emory University School of Medicine, and 4Atlanta Veterans Administration Medical Center, Atlanta, Georgia; 5California Emerging Infections Program, Oakland, California; 6Colorado Department of Public Health, Denver, Colorado; 7Connecticut Emerging Infections Program, Yale University, New Haven, Connecticut; 8Maryland Department of Health and Mental Hygiene, Baltimore, Maryland; 9Minnesota Department of Health, St Paul, Minnesota; 10New Mexico Emerging Infections Program, Santa Fe, New Mexico; 11New York State Health Department, Albany, and 12Monroe County Health Department, Rochester, New York; 13Oregon Public Health Division, Portland, Oregon; and 14Tennessee Department of Health and 15Department of Preventive Medicine, Vanderbilt University, Nashville, Tennessee
Background.Rates of influenza‐associated hospitalizations in the United States have been estimated using modeling techniques with data from pneumonia and influenza hospitalization discharge diagnoses, but they have not been directly estimated from laboratory‐positive cases.
Methods.We calculated overall, age‐specific, and site‐specific rates of laboratory‐positive, influenza‐associated hospitalization among adults and compared demographic and clinical characteristics and outcomes of hospitalized cases by season with use of data collected by the Emerging Infections Program Network during the 2005?2006 through 2007?2008 influenza seasons.
Results.Overall rates of adult influenza‐associated hospitalization per 100,000 persons were 9.9 during the 2005?2006 season, 4.8 during the 2006?2007 season, and 18.7 during the 2007?2008 season. Rates of hospitalization varied by Emerging Infections Program site and increased with increasing age. Higher overall and age‐specific rates of hospitalization were observed during influenza A (H3) predominant seasons and during periods of increased circulation of influenza B. More than 80% of hospitalized persons each season had 1 underlying medical condition, including chronic cardiovascular and metabolic diseases.
Conclusions.Rates varied by season, age, geographic location, and type/subtype of circulating influenza viruses. Influenza‐associated hospitalization surveillance is essential for assessing the relative severity of influenza seasons over time and the burden of influenza‐associated complications.
http://www.journals.uchicago.edu/doi/abs/10.1086/655904