tetano
Editor, Senior Moderator
Acute Med Surg
. 2022 Oct 5;9(1):e793.
doi: 10.1002/ams2.793. eCollection 2022 Jan-Dec.
A case of massive refractory diarrhea in a patient with COVID-19
Kentaro Shimizu[SUP] 1 [/SUP], Haruhiko Hirata[SUP] 2 [/SUP], Natsuko Tokuhira[SUP] 3 [/SUP], Akiko Ueda[SUP] 4 [/SUP], Daisuke Motooka[SUP] 5 [/SUP], Shota Nakamura[SUP] 5 [/SUP], Hiroshi Ogura[SUP] 1 [/SUP]
Affiliations
Abstract
Background: The new coronavirus disease (COVID-19) causes gastrointestinal symptoms as well as respiratory symptoms.
Case presentation: A 60-year-old man was transferred with respiratory difficulty. He was diagnosed as having COVID-19 and was intubated and placed on mechanical ventilation. He suffered from diarrhea from day 12 and produced a maximum of approximately 6,384 mL/day of watery diarrhea on day 21. He required massive transfusion. Adsorbents and pectin-containing oligomeric formulas were administered, which decreased the amount of diarrhea. Fecal metagenomic analysis showed the proportions of the genera Enterococcus and Staphylococcus were the most dominate at the genus level. The proportion of Bacteroidetes was <1%. Thereafter, his diarrhea decreased to several times, and he was transferred to another ward on day 104.
Conclusion: Therapy for intestinal complications as well as that for pneumonia might be important in treating COVID-19.
Keywords: COVID‐19; diarrhea; gastroenterology and hepatology; intensive care unit; nutrition; sepsis/multiple organ failure.
. 2022 Oct 5;9(1):e793.
doi: 10.1002/ams2.793. eCollection 2022 Jan-Dec.
A case of massive refractory diarrhea in a patient with COVID-19
Kentaro Shimizu[SUP] 1 [/SUP], Haruhiko Hirata[SUP] 2 [/SUP], Natsuko Tokuhira[SUP] 3 [/SUP], Akiko Ueda[SUP] 4 [/SUP], Daisuke Motooka[SUP] 5 [/SUP], Shota Nakamura[SUP] 5 [/SUP], Hiroshi Ogura[SUP] 1 [/SUP]
Affiliations
- PMID: 36225723
- PMCID: PMC9535351
- DOI: 10.1002/ams2.793
Abstract
Background: The new coronavirus disease (COVID-19) causes gastrointestinal symptoms as well as respiratory symptoms.
Case presentation: A 60-year-old man was transferred with respiratory difficulty. He was diagnosed as having COVID-19 and was intubated and placed on mechanical ventilation. He suffered from diarrhea from day 12 and produced a maximum of approximately 6,384 mL/day of watery diarrhea on day 21. He required massive transfusion. Adsorbents and pectin-containing oligomeric formulas were administered, which decreased the amount of diarrhea. Fecal metagenomic analysis showed the proportions of the genera Enterococcus and Staphylococcus were the most dominate at the genus level. The proportion of Bacteroidetes was <1%. Thereafter, his diarrhea decreased to several times, and he was transferred to another ward on day 104.
Conclusion: Therapy for intestinal complications as well as that for pneumonia might be important in treating COVID-19.
Keywords: COVID‐19; diarrhea; gastroenterology and hepatology; intensive care unit; nutrition; sepsis/multiple organ failure.