tetano
Editor, Senior Moderator
J Chin Med Assoc. 2011 Sep;74(9):425-7. Epub 2011 Sep 23.
Acute immune thrombocytopenic purpura in an adolescent with 2009 novel H1N1 influenza A virus infection.
Lee CY, Wu MC, Chen PY, Chou TY, Chan YJ.
Source
Department of Pediatrics, Chang-Bing Show Chwan Memorial Hospital, Changhua, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Abstract
Although both leukopenia and thrombocytopenia are not uncommon hematological findings among patients with novel 2009 H1N1 influenza virus infection, immune thrombocytopenic purpura has rarely been shown to be associated with this novel influenza A infection. Here, we describe a previously healthy adolescent who presented with fever, influenza-like symptoms and acute onset of generalized petechiae and active oral mucosa bleeding on the third day of his illness. Severe leukopenia and thrombocytopenia were found. There was neither malignancy nor blast cells found by bone marrow aspiration. Real-time reverse transcriptase polymerase chain reaction was positive for novel 2009 H1N1 influenza infection. Novel influenza-associated atypical immune thrombocytopenic purpura was diagnosed. The patient recovered uneventfully after oseltamivir and methylprednisolone therapy.
Copyright ? 2011. Published by Elsevier B.V.
PMID:
21962253
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21962253
Acute immune thrombocytopenic purpura in an adolescent with 2009 novel H1N1 influenza A virus infection.
Lee CY, Wu MC, Chen PY, Chou TY, Chan YJ.
Source
Department of Pediatrics, Chang-Bing Show Chwan Memorial Hospital, Changhua, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Abstract
Although both leukopenia and thrombocytopenia are not uncommon hematological findings among patients with novel 2009 H1N1 influenza virus infection, immune thrombocytopenic purpura has rarely been shown to be associated with this novel influenza A infection. Here, we describe a previously healthy adolescent who presented with fever, influenza-like symptoms and acute onset of generalized petechiae and active oral mucosa bleeding on the third day of his illness. Severe leukopenia and thrombocytopenia were found. There was neither malignancy nor blast cells found by bone marrow aspiration. Real-time reverse transcriptase polymerase chain reaction was positive for novel 2009 H1N1 influenza infection. Novel influenza-associated atypical immune thrombocytopenic purpura was diagnosed. The patient recovered uneventfully after oseltamivir and methylprednisolone therapy.
Copyright ? 2011. Published by Elsevier B.V.
PMID:
21962253
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21962253