Mary Wilson
New member
Published online March 8, 2021.
doi:10.1001/jama.2021.3976
Kimberly G. Blumenthal, MD, MSc[SUP]1[/SUP]; Lacey B. Robinson, MD, MPH[SUP]1[/SUP]; Carlos A. Camargo Jr, MD, DrPH[SUP]2[/SUP]; et al
Anaphylaxis to the mRNA COVID-19 vaccines is currently estimated to occur in 2.5 to 11.1 cases per million doses, largely in individuals with a history of allergy.[SUP]1[/SUP] Allergic concerns contribute to vaccine hesitancy; we investigated acute allergic reaction incidence after more than 60?000 mRNA COVID-19 vaccine administrations.
Methods
We prospectively studied Mass General Brigham (MGB) employees who received their first dose of an mRNA COVID-19 vaccine (12/16/2020-2/12/2021, with follow-up through 2/18/2021) (eMethods in the Supplement). For 3 days after vaccination, employees completed symptom surveys through a multipronged approach including email, text message, phone, and smartphone application links. Acute allergic reaction symptoms solicited included itching, rash, hives, swelling, and/or respiratory symptoms (eAppendix in the Supplement). ...
https://jamanetwork.com/journals/jama/fullarticle/2777417
doi:10.1001/jama.2021.3976
Kimberly G. Blumenthal, MD, MSc[SUP]1[/SUP]; Lacey B. Robinson, MD, MPH[SUP]1[/SUP]; Carlos A. Camargo Jr, MD, DrPH[SUP]2[/SUP]; et al
Anaphylaxis to the mRNA COVID-19 vaccines is currently estimated to occur in 2.5 to 11.1 cases per million doses, largely in individuals with a history of allergy.[SUP]1[/SUP] Allergic concerns contribute to vaccine hesitancy; we investigated acute allergic reaction incidence after more than 60?000 mRNA COVID-19 vaccine administrations.
Methods
We prospectively studied Mass General Brigham (MGB) employees who received their first dose of an mRNA COVID-19 vaccine (12/16/2020-2/12/2021, with follow-up through 2/18/2021) (eMethods in the Supplement). For 3 days after vaccination, employees completed symptom surveys through a multipronged approach including email, text message, phone, and smartphone application links. Acute allergic reaction symptoms solicited included itching, rash, hives, swelling, and/or respiratory symptoms (eAppendix in the Supplement). ...
https://jamanetwork.com/journals/jama/fullarticle/2777417