tetano
Editor, Senior Moderator
Acta Otolaryngol
. Mar-Apr 2022;142(3-4):333-339.
doi: 10.1080/00016489.2022.2062047. Epub 2022 Apr 24.
Patterns of self-reported recovery from chemosensory dysfunction following SARS-CoV-2 infection: insights after 1 year of the pandemic
Dakheelallah M Almutairi[SUP] 1 2 3 [/SUP], Abdulaziz H Almalki[SUP] 1 2 [/SUP], Ahmad A Mirza[SUP] 4 5 [/SUP], Mohammed J Khalifah[SUP] 1 2 [/SUP], Ammar A Aljefri[SUP] 1 2 [/SUP], Khalid A Alsalmi[SUP] 1 2 [/SUP], Majid S Al-Thaqafy[SUP] 1 6 7 [/SUP], Mohammed A Algarni[SUP] 1 2 3 [/SUP]
Affiliations
Abstract
Background: The coronavirus disease (COVID-19), due to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causes chemosensory dysfunction.
Aims/objectives: To determine the characteristics of chemosensory dysfunction and to identify factors associated with chemosensory complete recovery and time to recovery.
Materials and methods: This cross-sectional study included all patients presenting with chemosensory dysfunction and confirmed SARS-CoV-2 infection from May to August 2020 who underwent telemedicine follow-up after 1 year to assess their chemosensory recovery.
Results: A total of 372 patients were included, of which 53.8% were male. The mean age ± SD was 37.45 ± 13.44. The majority experienced combined (olfactory and gustatory) dysfunction (85.7%), and 315 patients (84.7%) had complete loss of chemosensory function. The independent predictors associated with a low likelihood of complete recovery were parosmia (aOR 0.16, p < .001), upper respiratory tract symptoms (aOR 0.28, p = .001), and dyspnoea (aOR 0.21, p < .001), whereas the factors associated with a long recovery period were parosmia (aOR 12.04, p = .002), headache (aOR 7.19, p = .007), and hypertension (aOR 7.76, p = .039).
Conclusions: A full recovery outcome was predominant. The presence of parosmia was linked to both an incomplete recovery and a long time to recovery.
Significance: Parosmia and respiratory symptoms are implicated in the incomplete recuperation of chemosensory function.
Keywords: COVID-19; SARS-CoV-2; chemosensory dysfunction; olfactory disorders; taste disorders.
. Mar-Apr 2022;142(3-4):333-339.
doi: 10.1080/00016489.2022.2062047. Epub 2022 Apr 24.
Patterns of self-reported recovery from chemosensory dysfunction following SARS-CoV-2 infection: insights after 1 year of the pandemic
Dakheelallah M Almutairi[SUP] 1 2 3 [/SUP], Abdulaziz H Almalki[SUP] 1 2 [/SUP], Ahmad A Mirza[SUP] 4 5 [/SUP], Mohammed J Khalifah[SUP] 1 2 [/SUP], Ammar A Aljefri[SUP] 1 2 [/SUP], Khalid A Alsalmi[SUP] 1 2 [/SUP], Majid S Al-Thaqafy[SUP] 1 6 7 [/SUP], Mohammed A Algarni[SUP] 1 2 3 [/SUP]
Affiliations
- PMID: 35621146
- DOI: 10.1080/00016489.2022.2062047
Abstract
Background: The coronavirus disease (COVID-19), due to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causes chemosensory dysfunction.
Aims/objectives: To determine the characteristics of chemosensory dysfunction and to identify factors associated with chemosensory complete recovery and time to recovery.
Materials and methods: This cross-sectional study included all patients presenting with chemosensory dysfunction and confirmed SARS-CoV-2 infection from May to August 2020 who underwent telemedicine follow-up after 1 year to assess their chemosensory recovery.
Results: A total of 372 patients were included, of which 53.8% were male. The mean age ± SD was 37.45 ± 13.44. The majority experienced combined (olfactory and gustatory) dysfunction (85.7%), and 315 patients (84.7%) had complete loss of chemosensory function. The independent predictors associated with a low likelihood of complete recovery were parosmia (aOR 0.16, p < .001), upper respiratory tract symptoms (aOR 0.28, p = .001), and dyspnoea (aOR 0.21, p < .001), whereas the factors associated with a long recovery period were parosmia (aOR 12.04, p = .002), headache (aOR 7.19, p = .007), and hypertension (aOR 7.76, p = .039).
Conclusions: A full recovery outcome was predominant. The presence of parosmia was linked to both an incomplete recovery and a long time to recovery.
Significance: Parosmia and respiratory symptoms are implicated in the incomplete recuperation of chemosensory function.
Keywords: COVID-19; SARS-CoV-2; chemosensory dysfunction; olfactory disorders; taste disorders.