tetano
Editor, Senior Moderator
Acta Obstet Gynecol Scand
. 2021 Apr 22.
doi: 10.1111/aogs.14160. Online ahead of print.
COVID-19 in pregnancy - characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries
Hilde Engjom[SUP] 1 2 [/SUP], Anna Jm Aabakke[SUP] 3 4 [/SUP], Kari Klungs?yr[SUP] 5 6 [/SUP], Teresia Svanvik[SUP] 7 [/SUP], Outi ?yr?s[SUP] 8 [/SUP], Eva Jonasdottir[SUP] 9 [/SUP], Lars Thurn[SUP] 10 [/SUP], Elin Jones[SUP] 11 [/SUP], Karin Pettersson[SUP] 11 [/SUP], Lill Trine Nyfl?t[SUP] 12 [/SUP], Iqbal Al-Zirqi[SUP] 12 [/SUP], Siri Vangen[SUP] 12 [/SUP], P?tur B J?l?usson[SUP] 1 [/SUP], Karin K?ll?n[SUP] 13 [/SUP], Mika Gissler[SUP] 14 [/SUP], Lone Krebs[SUP] 4 15 [/SUP]
Affiliations
Abstract
Introduction: Population-based studies about the consequences of SARS-CoV-2 infection (COVID-19) in pregnancy are few and have limited generalizability to the Nordic population and health care systems.
Material and methods: This study examines pregnant women with COVID-19 in the five Nordic countries. Pregnant women were included if they were admitted to hospital between March 1 and June 30, 2020 and had a positive SARS-CoV-2 PCR test 14 days or fewer prior to the admission. Cause of admission was classified as obstetric or COVID-19 related.
Results: In the study areas, 214 pregnant women with a positive test were admitted to hospital, of which 56 women needed hospital care due to COVID-19. The risk of admission due to COVID-19 was 0.4 per 1000 deliveries in Denmark, Finland, and Norway and 3.8 per 1000 deliveries in the Swedish regions. Women hospitalized because of COVID-19 were more frequently obese (P < 0.001) and had migrant background (P < 0.001) compared to the total population of women who delivered in 2018. Twelve women (21.4%) needed intensive care. Among the 56 women admitted due to COVID-19, 48 women delivered 51 infants. Preterm delivery (n=12, 25%, P < 0.001) and cesarean delivery (n=21, 43,8%, P < 0.001) were more frequent in women with COVID-19 compared to the women who delivered in 2018. No maternal deaths, stillbirths or neonatal deaths were reported.
Conclusions: The risk of admission due to COVID-19 disease in pregnancy was low in the Nordic countries. A fifth of the women required intensive care and we observed higher rates of preterm and cesarean deliveries. National public health policies appear to have had an impact on the risk of admission due to severe COVID-19 disease in pregnancy. Nordic collaboration is important in collecting robust data and assessing rare outcomes.
Keywords: COVID-19; Cohort studies; Obstetric delivery; Pregnancy; Pregnancy complications; Pregnancy outcome; Prospective studies; Severe acute respiratory syndrome coronavirus 2.
. 2021 Apr 22.
doi: 10.1111/aogs.14160. Online ahead of print.
COVID-19 in pregnancy - characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries
Hilde Engjom[SUP] 1 2 [/SUP], Anna Jm Aabakke[SUP] 3 4 [/SUP], Kari Klungs?yr[SUP] 5 6 [/SUP], Teresia Svanvik[SUP] 7 [/SUP], Outi ?yr?s[SUP] 8 [/SUP], Eva Jonasdottir[SUP] 9 [/SUP], Lars Thurn[SUP] 10 [/SUP], Elin Jones[SUP] 11 [/SUP], Karin Pettersson[SUP] 11 [/SUP], Lill Trine Nyfl?t[SUP] 12 [/SUP], Iqbal Al-Zirqi[SUP] 12 [/SUP], Siri Vangen[SUP] 12 [/SUP], P?tur B J?l?usson[SUP] 1 [/SUP], Karin K?ll?n[SUP] 13 [/SUP], Mika Gissler[SUP] 14 [/SUP], Lone Krebs[SUP] 4 15 [/SUP]
Affiliations
- PMID: 33885150
- DOI: 10.1111/aogs.14160
Abstract
Introduction: Population-based studies about the consequences of SARS-CoV-2 infection (COVID-19) in pregnancy are few and have limited generalizability to the Nordic population and health care systems.
Material and methods: This study examines pregnant women with COVID-19 in the five Nordic countries. Pregnant women were included if they were admitted to hospital between March 1 and June 30, 2020 and had a positive SARS-CoV-2 PCR test 14 days or fewer prior to the admission. Cause of admission was classified as obstetric or COVID-19 related.
Results: In the study areas, 214 pregnant women with a positive test were admitted to hospital, of which 56 women needed hospital care due to COVID-19. The risk of admission due to COVID-19 was 0.4 per 1000 deliveries in Denmark, Finland, and Norway and 3.8 per 1000 deliveries in the Swedish regions. Women hospitalized because of COVID-19 were more frequently obese (P < 0.001) and had migrant background (P < 0.001) compared to the total population of women who delivered in 2018. Twelve women (21.4%) needed intensive care. Among the 56 women admitted due to COVID-19, 48 women delivered 51 infants. Preterm delivery (n=12, 25%, P < 0.001) and cesarean delivery (n=21, 43,8%, P < 0.001) were more frequent in women with COVID-19 compared to the women who delivered in 2018. No maternal deaths, stillbirths or neonatal deaths were reported.
Conclusions: The risk of admission due to COVID-19 disease in pregnancy was low in the Nordic countries. A fifth of the women required intensive care and we observed higher rates of preterm and cesarean deliveries. National public health policies appear to have had an impact on the risk of admission due to severe COVID-19 disease in pregnancy. Nordic collaboration is important in collecting robust data and assessing rare outcomes.
Keywords: COVID-19; Cohort studies; Obstetric delivery; Pregnancy; Pregnancy complications; Pregnancy outcome; Prospective studies; Severe acute respiratory syndrome coronavirus 2.