tetano
Editor, Senior Moderator
Acta Anaesthesiol Scand
. 2021 Jan 27.
doi: 10.1111/aas.13785. Online ahead of print.
Characteristics, management and survival of ICU patients with coronavirus disease-19 in Norway, March - June 2020. A prospective observational study
Jon Henrik Laake[SUP] 1 2 [/SUP], Eirik Alnes Buanes[SUP] 3 4 [/SUP], Milada Cvancarova Sm?stuen[SUP] 5 [/SUP], Reidar Kv?le[SUP] 3 4 6 [/SUP], Brita Fosser Olsen[SUP] 7 8 [/SUP], Tone Rust?en[SUP] 2 9 [/SUP], Kristian Strand[SUP] 10 [/SUP], Vibecke S?rensen[SUP] 11 [/SUP], Kristin Hofs?[SUP] 2 12 [/SUP]
Affiliations
Abstract
Background: Norwegian hospitals have operated within capacity during the COVID-19 pandemic. We present patient and management characteristics, and outcomes for the entire cohort of adult (> 18 years) COVID-19 patients admitted to Norwegian intensive care units (ICU) from 10 March to 19 June 2020.
Methods: Data were collected from The Norwegian intensive care and pandemic registry (NIPaR). Demographics, co-morbidities, management characteristics and outcomes are described. ICU length of stay (LOS) was analysed with linear regression, and associations between risk factors and mortality were quantified using Cox regression.
Results: In total, 217 patients were included. The male to female ratio was 3:1 and the median age was 63 years. A majority (70%) had one or more co-morbidities, most frequently cardiovascular disease (39%), chronic lung disease (22%), diabetes mellitus (20%), and obesity (17%). Most patients were admitted for acute hypoxaemic respiratory failure (AHRF)(91%) and invasive mechanical ventilation (MV) was used in 86%, prone ventilation in 38% and 25% of patients received a tracheostomy. Vasoactive drugs were used in 79% and renal replacement therapy in 15%. Median ICU LOS and time of MV was 14.0 and 12.0 days. At end of follow-up 45 patients (21%) were dead. Age, co-morbidities and severity of illness at admission were predictive of death. Severity of AHRF and male gender were associated with LOS.
Conclusions: In this national cohort of COVID-19 patients, mortality was low and attributable to known risk factors. Importantly, prolonged length-of-stay must be taken into account when planning for resource allocation for any next surge.
Keywords: ARDS; ICU; Norway; SARS-CoV2; covid-19; mechanical ventilation; national cohort
. 2021 Jan 27.
doi: 10.1111/aas.13785. Online ahead of print.
Characteristics, management and survival of ICU patients with coronavirus disease-19 in Norway, March - June 2020. A prospective observational study
Jon Henrik Laake[SUP] 1 2 [/SUP], Eirik Alnes Buanes[SUP] 3 4 [/SUP], Milada Cvancarova Sm?stuen[SUP] 5 [/SUP], Reidar Kv?le[SUP] 3 4 6 [/SUP], Brita Fosser Olsen[SUP] 7 8 [/SUP], Tone Rust?en[SUP] 2 9 [/SUP], Kristian Strand[SUP] 10 [/SUP], Vibecke S?rensen[SUP] 11 [/SUP], Kristin Hofs?[SUP] 2 12 [/SUP]
Affiliations
- PMID: 33501998
- DOI: 10.1111/aas.13785
Abstract
Background: Norwegian hospitals have operated within capacity during the COVID-19 pandemic. We present patient and management characteristics, and outcomes for the entire cohort of adult (> 18 years) COVID-19 patients admitted to Norwegian intensive care units (ICU) from 10 March to 19 June 2020.
Methods: Data were collected from The Norwegian intensive care and pandemic registry (NIPaR). Demographics, co-morbidities, management characteristics and outcomes are described. ICU length of stay (LOS) was analysed with linear regression, and associations between risk factors and mortality were quantified using Cox regression.
Results: In total, 217 patients were included. The male to female ratio was 3:1 and the median age was 63 years. A majority (70%) had one or more co-morbidities, most frequently cardiovascular disease (39%), chronic lung disease (22%), diabetes mellitus (20%), and obesity (17%). Most patients were admitted for acute hypoxaemic respiratory failure (AHRF)(91%) and invasive mechanical ventilation (MV) was used in 86%, prone ventilation in 38% and 25% of patients received a tracheostomy. Vasoactive drugs were used in 79% and renal replacement therapy in 15%. Median ICU LOS and time of MV was 14.0 and 12.0 days. At end of follow-up 45 patients (21%) were dead. Age, co-morbidities and severity of illness at admission were predictive of death. Severity of AHRF and male gender were associated with LOS.
Conclusions: In this national cohort of COVID-19 patients, mortality was low and attributable to known risk factors. Importantly, prolonged length-of-stay must be taken into account when planning for resource allocation for any next surge.
Keywords: ARDS; ICU; Norway; SARS-CoV2; covid-19; mechanical ventilation; national cohort