tetano
Editor, Senior Moderator
Acad Radiol
. 2020 Jul 30;S1076-6332(20)30454-2.
doi: 10.1016/j.acra.2020.07.031. Online ahead of print.
Imaging findings of SARS-CoV-2 infection in pediatrics: A systematic review of coronavirus disease 2019 (COVID-19) in 850 patients
Sanaz Katal[SUP] 1 [/SUP], Sean K Johnston[SUP] 2 [/SUP], Jennifer H Johnston[SUP] 3 [/SUP], Ali Gholamrezanezhad[SUP] 4 [/SUP]
Affiliations
Abstract
Rationale and objectives: Children with COVID-19 seem to have a relatively milder disease and better prognosis; however, severe disease or death could still occur in this age group. Although the knowledge on the clinical and epidemiology of COVID-19 in pediatric patients is being accumulated rapidly, relevant comprehensive review on its radiological manifestations is still lacking. The present article reviews the radiological characteristics of COVID-19 in pediatrics, based on the previous studies.
Materials and methods: We conducted a systematic literature search for published articles by using Medline, Scopus, Google Scholar and Embase online databases. All studies describing CT findings of COVID-19 in pediatrics (<18years) were included.
Results: A total of 39 studies with 850 pediatric patients were reviewed. 225 (26.5%) of patients had normal CT findings. Ground-glass opacities and consolidations were the most common CT abnormalities (384/625, 61.5%). Other findings were halo sign, interstitial opacities, bronchial wall thickening, and crazy-paving sign. Approximately 55% of patients had unilateral pulmonary findings. Most studies found peripheral and lower-lobe distribution to be a prominent imaging finding.
Conclusion: Our study showed that imaging findings in children were often milder and more focal than adults, typically as ground-glass opacities and consolidations with unilateral lower-lobe predominance, which have been regressed during the recovery time. A balance must be struck between the risk of radiation and the need for chest CT. If still necessary, low-dose CT is more appropriate in this age group. Albeit, due to the limited number of reported pediatrics with COVID-19, and the lack of consistency in CT descriptors, further work is still needed in this regard.
Keywords: COVID-19; CT-scan; Chest imaging; Children; Lung; Pediatrics; Pneumonia; Radiation; SARS-CoV-2.
. 2020 Jul 30;S1076-6332(20)30454-2.
doi: 10.1016/j.acra.2020.07.031. Online ahead of print.
Imaging findings of SARS-CoV-2 infection in pediatrics: A systematic review of coronavirus disease 2019 (COVID-19) in 850 patients
Sanaz Katal[SUP] 1 [/SUP], Sean K Johnston[SUP] 2 [/SUP], Jennifer H Johnston[SUP] 3 [/SUP], Ali Gholamrezanezhad[SUP] 4 [/SUP]
Affiliations
- PMID: 32773328
- DOI: 10.1016/j.acra.2020.07.031
Abstract
Rationale and objectives: Children with COVID-19 seem to have a relatively milder disease and better prognosis; however, severe disease or death could still occur in this age group. Although the knowledge on the clinical and epidemiology of COVID-19 in pediatric patients is being accumulated rapidly, relevant comprehensive review on its radiological manifestations is still lacking. The present article reviews the radiological characteristics of COVID-19 in pediatrics, based on the previous studies.
Materials and methods: We conducted a systematic literature search for published articles by using Medline, Scopus, Google Scholar and Embase online databases. All studies describing CT findings of COVID-19 in pediatrics (<18years) were included.
Results: A total of 39 studies with 850 pediatric patients were reviewed. 225 (26.5%) of patients had normal CT findings. Ground-glass opacities and consolidations were the most common CT abnormalities (384/625, 61.5%). Other findings were halo sign, interstitial opacities, bronchial wall thickening, and crazy-paving sign. Approximately 55% of patients had unilateral pulmonary findings. Most studies found peripheral and lower-lobe distribution to be a prominent imaging finding.
Conclusion: Our study showed that imaging findings in children were often milder and more focal than adults, typically as ground-glass opacities and consolidations with unilateral lower-lobe predominance, which have been regressed during the recovery time. A balance must be struck between the risk of radiation and the need for chest CT. If still necessary, low-dose CT is more appropriate in this age group. Albeit, due to the limited number of reported pediatrics with COVID-19, and the lack of consistency in CT descriptors, further work is still needed in this regard.
Keywords: COVID-19; CT-scan; Chest imaging; Children; Lung; Pediatrics; Pneumonia; Radiation; SARS-CoV-2.