tetano
Editor, Senior Moderator
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 May;31(5):485-488.
[A survey on serological epidemiology of influenza A (H1N1) 2009 in Beijing.]
[Article in Chinese]
Yang P, Huang F, Shi WX, Lu GL, Tian LL, Cui SJ, Zhang X, Li S, Liu BW, Deng Y, Pang XH, Wang QY.
Institute of Infectious and Endemic Diseases Control, Beijing Center for Disease Contorl and Prevention, Beijing 100013, China.
Abstract
OBJECTIVE: To investigate the immunological level against influenza A (H1N1) 2009 in Beijing and provide evidence to evaluate the developing trend of the disease.
METHODS: Between Nov. 27, 2009 and Dec. 23, 2009, subjects were randomly selected from patients in hospitals (infectious and respiratory diseases related departments were excluded), volunteers in blood donation center and healthy subjects attending the physical examination center. Questionnaire survey was conducted and serum samples were collected to detect the hemagglutination-inhibition (HI) antibody against influenza A (H1N1) 2009 virus.
RESULTS: 856 subjects participated in this survey, and 127 showed positive HI antibody to this pandemic virus. The proportions of sero-positivity among 0 - 5, 6 - 17, 18 - 55, ≥ 56 year olds were 14.5%, 19.4%, 17.4% and 8.0% respectively (P = 0.009). There was no significant difference in the sero-positivity between males and females (P = 0.693). The age-adjusted positive rate was 15.8% in the population of Beijing. By multivariate logistic regression analysis, factors as age, acute respiratory symptoms and the rate of pandemic (H1N1) 2009 vaccination were significantly associated with sero-positivity of HI antibody to the influenza A (H1N1) 2009 virus.
CONCLUSION: Above 15% of the population in Beijing showed protective antibody against influenza A (H1N1) 2009 virus, indicating the development of immunological barrier to this disease had been formed, to some extent.
PMID: 21163020 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21163020
[A survey on serological epidemiology of influenza A (H1N1) 2009 in Beijing.]
[Article in Chinese]
Yang P, Huang F, Shi WX, Lu GL, Tian LL, Cui SJ, Zhang X, Li S, Liu BW, Deng Y, Pang XH, Wang QY.
Institute of Infectious and Endemic Diseases Control, Beijing Center for Disease Contorl and Prevention, Beijing 100013, China.
Abstract
OBJECTIVE: To investigate the immunological level against influenza A (H1N1) 2009 in Beijing and provide evidence to evaluate the developing trend of the disease.
METHODS: Between Nov. 27, 2009 and Dec. 23, 2009, subjects were randomly selected from patients in hospitals (infectious and respiratory diseases related departments were excluded), volunteers in blood donation center and healthy subjects attending the physical examination center. Questionnaire survey was conducted and serum samples were collected to detect the hemagglutination-inhibition (HI) antibody against influenza A (H1N1) 2009 virus.
RESULTS: 856 subjects participated in this survey, and 127 showed positive HI antibody to this pandemic virus. The proportions of sero-positivity among 0 - 5, 6 - 17, 18 - 55, ≥ 56 year olds were 14.5%, 19.4%, 17.4% and 8.0% respectively (P = 0.009). There was no significant difference in the sero-positivity between males and females (P = 0.693). The age-adjusted positive rate was 15.8% in the population of Beijing. By multivariate logistic regression analysis, factors as age, acute respiratory symptoms and the rate of pandemic (H1N1) 2009 vaccination were significantly associated with sero-positivity of HI antibody to the influenza A (H1N1) 2009 virus.
CONCLUSION: Above 15% of the population in Beijing showed protective antibody against influenza A (H1N1) 2009 virus, indicating the development of immunological barrier to this disease had been formed, to some extent.
PMID: 21163020 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21163020