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A novel method for increased yield of immunocompetent virus for vaccine production

tetano

Editor, Senior Moderator
World J Microbiol Biotechnol. 1991 Sep;7(5):567-70. doi: 10.1007/BF00368362.
A novel method for increased yield of immunocompetent virus for vaccine production.
Qureshi AA.
Author information
Abstract

Cultured human cells exposed to the pesticide emulsifier Atlox, 6 to 8 h prior to Infection with influenza A virus, increased virus production approximately 10-fold. Antibodies against the 'enhanced virus' neutralized plaque formation and reacted equally well with non-enhanced virus in serological tests (haemagglutination-inhibition and radioimmunoassays). The procedure has great potential in cutting costs of production for some virus vaccines.

PMID:
24425199
[PubMed]

http://www.ncbi.nlm.nih.gov/pubmed/24425199
 
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