tetano
Editor, Senior Moderator
Fitoterapia. 2015 Oct 23. pii: S0367-326X(15)30103-9. doi: 10.1016/j.fitote.2015.10.009. [Epub ahead of print]
[h=1]A novel isocoumarin with anti-influenza virus activity from Strobilanthes cusia.[/h] Gu W[SUP]1[/SUP], Wang W[SUP]2[/SUP], Li XN[SUP]3[/SUP], Zhang Y[SUP]3[/SUP], Wang LP[SUP]1[/SUP], Yuan CM[SUP]1[/SUP], Huang LJ[SUP]1[/SUP], Hao XJ[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Strobilanthes A (1), a novel isocoumarin with an unusual tetrahydro-4H-pyran-4-one moiety fused isocoumarin core skeleton, together with a known compound (2) was isolated from Strobilanthes cusia. Its chemical structures were elucidated by 2D NMR spectroscopy, mass spectrometry and single-crystal X-ray diffraction analysis. The biosynthetic pathway of 1 could be supposed to be originally derived from 3-methylisocoumarin, a product of AA-MA pathway. Both of two compounds displayed anti-influenza virus activity in vitro.
Copyright ? 2015. Published by Elsevier B.V.
[h=4]KEYWORDS:[/h] Anti-influenza virus activity; Novel isocoumarin; Strobilanthes cusia; Unprecedented skeleton
PMID: 26506123 [PubMed - as supplied by publisher]
[h=1]A novel isocoumarin with anti-influenza virus activity from Strobilanthes cusia.[/h] Gu W[SUP]1[/SUP], Wang W[SUP]2[/SUP], Li XN[SUP]3[/SUP], Zhang Y[SUP]3[/SUP], Wang LP[SUP]1[/SUP], Yuan CM[SUP]1[/SUP], Huang LJ[SUP]1[/SUP], Hao XJ[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Strobilanthes A (1), a novel isocoumarin with an unusual tetrahydro-4H-pyran-4-one moiety fused isocoumarin core skeleton, together with a known compound (2) was isolated from Strobilanthes cusia. Its chemical structures were elucidated by 2D NMR spectroscopy, mass spectrometry and single-crystal X-ray diffraction analysis. The biosynthetic pathway of 1 could be supposed to be originally derived from 3-methylisocoumarin, a product of AA-MA pathway. Both of two compounds displayed anti-influenza virus activity in vitro.
Copyright ? 2015. Published by Elsevier B.V.
[h=4]KEYWORDS:[/h] Anti-influenza virus activity; Novel isocoumarin; Strobilanthes cusia; Unprecedented skeleton
PMID: 26506123 [PubMed - as supplied by publisher]