tetano
Editor, Senior Moderator
J Perinatol. 2013 Sep 19. doi: 10.1038/jp.2013.110. [Epub ahead of print]
A multicenter cohort study of pregnancy outcomes among women with laboratory-confirmed H1N1 influenza.
Naresh A, Fisher BM, Hoppe KK, Catov J, Xu J, Hart J, Lynch AM, Gibbs R, Eschenbach D, Gravett M, Beigi RH.
Source
Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Abstract
Objective:To evaluate associations between laboratory-confirmed 2009 H1N1 influenza infection and obstetric and neonatal outcomes.Study design:A multicenter cohort study was performed comparing laboratory-confirmed cases of 2009 H1N1 infection during pregnancy (N=142) with matched controls (N=710). Subanalysis was also performed comparing severely infected (hospitalized) women with controls.Result:No outcome differences were noted in comparing all women with H1N1 with controls. Women with severe infection had a higher incidence of delivering a small for gestational age (SGA) infant: 18.8% (6/32) versus 7.4% (52/707), adjusted odds ratio 2.35 (95% confidence interval 1.03, 5.36, P=0.02). Mean birth weight was 3013.0 g among severely infected women and 3223.3 g in controls (P=0.08), and incidence of preterm delivery was 25.0% (8/32) and 11.6% (82/710) (P=0.08), respectively.Conclusion
regnant women with mild clinical illness secondary to 2009 H1N1 were not at a greater risk of adverse pregnancy outcomes. However, severely infected women were more likely to deliver SGA infants.Journal of Perinatology advance online publication, 19 September 2013; doi:10.1038/jp.2013.110.
PMID:
24051575
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24051575
A multicenter cohort study of pregnancy outcomes among women with laboratory-confirmed H1N1 influenza.
Naresh A, Fisher BM, Hoppe KK, Catov J, Xu J, Hart J, Lynch AM, Gibbs R, Eschenbach D, Gravett M, Beigi RH.
Source
Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Abstract
Objective:To evaluate associations between laboratory-confirmed 2009 H1N1 influenza infection and obstetric and neonatal outcomes.Study design:A multicenter cohort study was performed comparing laboratory-confirmed cases of 2009 H1N1 infection during pregnancy (N=142) with matched controls (N=710). Subanalysis was also performed comparing severely infected (hospitalized) women with controls.Result:No outcome differences were noted in comparing all women with H1N1 with controls. Women with severe infection had a higher incidence of delivering a small for gestational age (SGA) infant: 18.8% (6/32) versus 7.4% (52/707), adjusted odds ratio 2.35 (95% confidence interval 1.03, 5.36, P=0.02). Mean birth weight was 3013.0 g among severely infected women and 3223.3 g in controls (P=0.08), and incidence of preterm delivery was 25.0% (8/32) and 11.6% (82/710) (P=0.08), respectively.Conclusion
regnant women with mild clinical illness secondary to 2009 H1N1 were not at a greater risk of adverse pregnancy outcomes. However, severely infected women were more likely to deliver SGA infants.Journal of Perinatology advance online publication, 19 September 2013; doi:10.1038/jp.2013.110.PMID:
24051575
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24051575