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A Hypothesis: Supplementation with Mushroom-Derived Active Compound Modulates Immunity and Increases Survival in Response to Influenza Virus (H1N1) In

tetano

Editor, Senior Moderator
Evid Based Complement Alternat Med. 2011;2011:252501. Epub 2011 Mar 20.
A Hypothesis: Supplementation with Mushroom-Derived Active Compound Modulates Immunity and Increases Survival in Response to Influenza Virus (H1N1) Infection.
Chunchao H, Guo JY.
Source

School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Abstract

We hypothesize that the mushroom-derived active compound may be a potential strategy for increasing survival in response to influenza virus (H1N1) infection through the stimulation of host innate immune response. The validity of the hypothesis can be tested by immune response to influenza infection as seen through survival percentage, virus clearance, weight loss, natural killer cell cytotoxicity, Tumor Necrosis Factor-α (TNF-α) and Interferon-gamma (IFN-γ) levels, lytic efficiency in the spleens of mice and inducible nitric oxide synthase mRNA expressions in RAW 264.7 murine macrophage cells. The hypothesis may improve people's quality of life, reduce the medical cost of our healthcare system and eliminate people's fears of influenza outbreak.

PMID:
21660092
[PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/21660092
 
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