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Journal of Applied Microbiology 2001, 91, 572-579
A History of Influenza
C.W. Potter
Division of Molecular and Genetic Medicine, University of Shef?eld Medical School, Shef?eld, UK and
Department of Pathology, Perak College of Medicine, Ipoh, Perak Darul Ridzuan, Malaysia
627/11/00: received 9 August 2000, revised 20 December 2000 and accepted 30 June 2001
C.W. Potter
Division of Molecular and Genetic Medicine, University of Shef?eld Medical School, Shef?eld, UK and
Department of Pathology, Perak College of Medicine, Ipoh, Perak Darul Ridzuan, Malaysia
627/11/00: received 9 August 2000, revised 20 December 2000 and accepted 30 June 2001
1. SUMMARY
From the history of influenza epidemics and pandemics,
which can be traced back with some accuracy for the past
three hundred years, and with less certainty before this
time, it is apparent that outbreaks occur somewhere in the
world in most years. Annual epidemics are due to antigenic
drift; and pandemics, occurring at 10 to 50 years intervals,
are due to new virus subtypes resulting from virus
reassortment. Nothing has been introduced during the past
100 years to affect the recurrent pattern of epidemics and
pandemics; and our future in the new century is clearly
indicated by our past. This past experience is reviewed in
the present paper. . . . .
which can be traced back with some accuracy for the past
three hundred years, and with less certainty before this
time, it is apparent that outbreaks occur somewhere in the
world in most years. Annual epidemics are due to antigenic
drift; and pandemics, occurring at 10 to 50 years intervals,
are due to new virus subtypes resulting from virus
reassortment. Nothing has been introduced during the past
100 years to affect the recurrent pattern of epidemics and
pandemics; and our future in the new century is clearly
indicated by our past. This past experience is reviewed in
the present paper. . . . .
hat-tip to gsgs
link: http://www.blackwell-synergy.com/doi/pdf/10.1046/j.1365-2672.2001.01492.x?cookieSet=1
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