tetano
Editor, Senior Moderator
J Infect Chemother. 2014 May 20. pii: S1341-321X(14)00174-3. doi: 10.1016/j.jiac.2014.04.008. [Epub ahead of print]
A case of community-acquired pneumonia due to influenza A virus and Nocardia farcinica co-infection.
Sawai T1, Yoshioka S2, Matsuo N2, Suyama N2, Kohno S3.
Author information
Abstract
Nocardia spp. has not been reported previously as a cause of post-influenza pneumonia. Here we present a first case of post-influenza bacterial pneumonia due to Nocardia farcinica. Initial reason for hospitalization of the 90 year old female patient was a pneumonia with the symptoms of fever and productive cough. A rapid test for influenza antigen was positive for influenza A virus. Treatment with Zanamivir and piperacillin was initiated. However, after 1 week of treatment, the infiltration shadows on chest X-ray had worsened. Because the expectorated sputum collected on admission for culture was found to be positive for Nocardia spp., piperacillin was replaced with trimethoprim/sulfamethoxazole, and a chest X-ray showed some improvement. Although pulmonary nocardiosis with co-infection with influenza A is extremely rare, clinicians should be alert to the possibility.
Copyright ? 2014 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
KEYWORDS:
Co-infection, Influenza, Nocardia farcinica, Post-influenza bacterial pneumonia
PMID:
24855916
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24855916
A case of community-acquired pneumonia due to influenza A virus and Nocardia farcinica co-infection.
Sawai T1, Yoshioka S2, Matsuo N2, Suyama N2, Kohno S3.
Author information
Abstract
Nocardia spp. has not been reported previously as a cause of post-influenza pneumonia. Here we present a first case of post-influenza bacterial pneumonia due to Nocardia farcinica. Initial reason for hospitalization of the 90 year old female patient was a pneumonia with the symptoms of fever and productive cough. A rapid test for influenza antigen was positive for influenza A virus. Treatment with Zanamivir and piperacillin was initiated. However, after 1 week of treatment, the infiltration shadows on chest X-ray had worsened. Because the expectorated sputum collected on admission for culture was found to be positive for Nocardia spp., piperacillin was replaced with trimethoprim/sulfamethoxazole, and a chest X-ray showed some improvement. Although pulmonary nocardiosis with co-infection with influenza A is extremely rare, clinicians should be alert to the possibility.
Copyright ? 2014 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
KEYWORDS:
Co-infection, Influenza, Nocardia farcinica, Post-influenza bacterial pneumonia
PMID:
24855916
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24855916