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Discussion of Antiviral activity of herbs (Sambucus FormosanaNakai, etc)

Emily

Editor, Senior Moderator
https://www.sciencedirect.com/scienc...68170219304198
Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63

Author:Jing-Ru Weng,Chen-Sheng Lin,Hsueh-Chou Lai,Yu-Ping Lin,Ching-Ying Wang,Yu-Chi Tsai,Kun-Chang Wu,Su-Hua Huang,Cheng-Wen Lin
Publication:Virus Research
Publisher:Elsevier
Date:November 2019
? 2019 Elsevier B.V. All rights reserved.

NL63 uses same receptor for entry as SARS and likely pHCoV-2019:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142358/
 
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Should we be concerned with taking elderberry and possibly helping feed a cytokine storm?

Of course, I can't give advice, but I wish I did have a clear answer on that even for myself that I could share. If you look at Bertrand's link there are a lot of articles exploring the complexity of the cytokine storm reaction.
 

As with all herbs (which can be medicines) the advice of a qualified doctor with knowledge of your personal history and a complete understanding of all interactions should be taken. There is a similar discussion about this here: https://flutrackers.com/forum/forum...orum/827819-discussion-2019-ncov-therapeutics

Even with the above study by Eric Yarnell I can see that licorice is recommended for some diseases - and, as far as I am aware, this increases blood pressure and would be contra indicated for many people.
 
Merci, vu les engagements de Wikipedia, dans cette crise, ces fiches sont ? niveau ?

https://en.wikipedia.org/wiki/Cytokine_release_syndrome
https://de.wikipedia.org/wiki/Zytokinsturm
https://fr.wikipedia.org/wiki/Choc_cytokinique
Vu le niveau de ces trois fiches , il me semble pr?f?rable de lire ceci :
Bien qu'il existe des preuves suffisantes pour montrer l'importance des temp?tes de cytokines dans les infections aigu?s s?v?res, peu a ?t? r?alis? ? ce jour pour pr?venir et am?liorer les r?sultats cliniques. Il existe actuellement des options de traitement
https://zh.wikipedia.org/wiki/細胞素風暴
 
Thanks for everyone's interest! I retitled this thread a bit so it could cover other herbs with antiviral research being done. We have used elderberry since reading about it here during pH1N1. We use it like Frozenthunderbolt suggested and that is infrequently and per label directions as far as dose. We stick with well-known brands bought from a large supermarket chain. I think it is possible that immune boosting herbs and mushrooms could make allergic/inflammatory symptoms worse based on my own experiences with that. It can be difficult to tell the difference between infections and allergies early on when symptoms are very mild.
Right now in the Puget Sound area near Seattle, most OTC remedies of all kinds are selling out, even basic decongestant sprays and saline sprays that don't seem related to COVID-19 symptoms. People are buying it all. We might see unrelated sinus allergies that people use OTC's to nip in the bud progressing to needing medical treatment. The other side is that people may start using things they never use and overuse these products since they fear COVID-19.
 
Merci, ?crire en ce lieu est un acte d'une grande difficult?, surtout qu'internet a de la m?moire. Nous sommes face ? un mauvais rhume, qui sera trait? comme un mauvais rhume en x lieux. Il y a d?j? la liste des mauvais traitements ? faire et diffuser, voir ibuprof?ne. Ce qui est primordial me semble d'indiquer ce qui peut fait pour que cela reste un mauvais rhume. Donc, c'est quoi le r?gime alimentaire, par exemple, en x lieux ? Les produits ferment?s sont ? recommander, ceux ? base de lait , etc ? Toutes les m?res doivent se poser la question, on leur dit quoi ? Faites comme d'habitude ou essayer de faire comme ceci ? Inclure les confitures de certains fruits, cela me semble une recommandation acceptable , par exemple.
 
Excellent points, Bertrand. Chicken was totally sold out in a big grocery store I was at yesterday. I think a lot people rely on chicken soup when they have colds. Many frozen vegetables were gone, too. Elderberry jams aren't routinely stocked here in the U.S., and some sources online are gone or are price-gouging. I saw a small farm source, but I bet that will be gone soon, too.
One caution about wild elderberry use in case this is still going on in the summer, they are somewhat toxic in the raw state and twigs, roots and leaves can be very toxic.
https://www.cdc.gov/mmwr/preview/mmwrhtml/00000311.htm
Poisoning from Elderberry Juice -- California

On August 26, 1983, eight people with acute gastrointestinal and neurologic symptoms were flown by helicopter to a Monterey, California, hospital. Earlier that day, they had attended a gathering for 25 persons of a religious/philosophic group in a remote area of Monterey County. Within 15 minutes after drinking refreshments, 11 persons began to have nausea and vomiting. The eight persons most ill reported nausea, vomiting, abdominal cramps, and weakness. Some also complained of dizziness and numbness; one was stuporous and was hospitalized. Arterial blood gases were normal for all eight, as were serum cyanide levels (reported later). The San Francisco Bay Area Regional Poison Control Center was promptly consulted regarding treatment for possible cyanide poisoning, but specific treatment was not given because 4 hours had elapsed since exposure, blood gases were normal, and the patients were stable. All recovered quickly, including the patient hospitalized overnight.
Investigation by the Monterey County Health Department revealed that staff at the religious center had gathered local, wild elderberries 2 days before the outbreak and had prepared juice from them the next day. Bunches of berries were crushed with their leaves and branches in a stainless-steel press. Apple juice, water, and sugar were added, and the mixture was stored overnight. The drink was served the next day in a stainless-steel pot to the group of 25 persons. Severity of illness correlated with the amount of elderberry juice consumed; those who drank only tea remained well. The hospitalized person had consumed five glasses of the juice; the others, much less.
Editorial Note

Editorial Note: The indigenous elder tree of the western United States, Sambucus mexicana, can grow to 30 feet and produces small (1/4-inch), globular, nearly black berries that can be covered with a white bloom at maturity. The berries are juicy and edible when mature. The cooked berries are commonly eaten in pies and jams, and berry juice can be fermented into wine. The fresh leaves, flowers, bark, young buds, and roots contain a bitter alkaloid and also a glucoside that, under certain conditions, can produce hydrocyanic acid. The amount of acid produced is usually greatest in young leaves. There may be other toxic constituents in this plant. The root is probably the most poisonous and may be responsible for occasional pig deaths; cattle and sheep have died after eating leaves and young shoots.
Although a review of the medical literature revealed no other reports of elderberry juice poisoning in the past 20 years, there are older, anecdotal reports of poisoning in children from the related elder, S. canadensis. The religious center staff has been advised that, while elderberries may be safe to consume, particularly if cooked (uncooked berries may produce nausea), leaves and stems should not be crushed in when making juice. Reported in California Morbidity (February 24, 1984) by S Kunitz, MD, RJ Melton, MD, T Updyke, Monterey County Health Dept, D Breedlove, PhD, California Academy of Sciences, San Francisco, SB Werner, MD, California State Dept of Health Svcs. Bibliography Casarett LJ, Doull J, eds. Toxicology: the basic science of poisons. New York: Macmillan Publishing Company, 1975. Kingsbury JM. Poisonous plants of the United States and Canada. Englewood Cliffs, New Jersey: Prentice-Hall, 1964. Millspaugh CF. American medicinal plants. New York: Dover Publications, Inc. Muenscher WC. Poisonous plants of the United States. New York: Macmillan Company, 1951. Osol A, Farrar GE. The Dispensatory of the United States of America. 25th ed. Philadelphia: JB Lippincott Company, 1955. Pammel LH. A manual of poisonous plants. Cedar Rapids, Iowa: The Torch Press, 1911.
Disclaimer All MMWR HTML documents published before January 1993 are electronic conversions from ASCII text into HTML. This conversion may have resulted in character translation or format errors in the HTML version. Users should not rely on this HTML document, but are referred to the original MMWR paper copy for the official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800. Contact GPO for current prices.
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Page converted: 08/05/98
 
Je souhaitais ?clairer, ce qui sera ou pourra ?tre fait, avant de voir, un m?decin. Mais, ensuite, il est recommand? quoi comme r?gime alimentaire, pour les patients des diverses tranches d'?ge et les personnels civils ou militaires en zone concern?e...
On a des donn?es sur les r?sultats en fonction des r?gimes alimentaires, dont v?gan ?
Je me souviens, en ce lieu, de textes sur Portulaca oleracea .
On recommande quoi ? toutes les personnes en surpoids, un facteur de risque? de faire comme d'habitude ou ?
Les nutritionnistes se sentent concerner ou pas ?
 
Thank you for the information about portulaca oleracea Bertrand, am I correct in thinking it may be useful in the same way as Resveratrol from japanese knotweed?
Merci beaucoup
 
vous ?tes un coquin, je sugg?re une plante pour une salade et vous d'office, vous souhaitez celle pour les principes actifs .

https://scholar.google.com/scholar?o...lookup=0&hl=fr

https://journals.plos.org/plosone/browse/ethnobotany

je me demande comment expliquer la situation au Japon, ils savent manger ou ?
Pour le fun: quand on voie des essais clinique avec de la vitamine C en intraveineuse, il n'y a rien ? conseiller d'autres que de prendre des comprim?s et ou des intraveineuses?

Pour ma part , j'ai augment?, de fa?on significative, ma dose journali?re, de cardosine ...
 
Portulaca oleracea, (purslane common name here), is an amazing herb! I enjoyed reading up on it, thanks. It’s not readily available or appreciated in the US. A few specialty farmers markets might have it and some people cultivate or gather it wild. Mostly it is considered an invasive weed even though Pacific Northwest natives gathered it as food prior to the arrival of Europeans. Thoreau wrote about gathering it for a meal in 1840, so it is a shame it fell out of favor as food.

I’ll keep an eye out for it on walks. The site below has a warning about a similar plant that is poisonous.
https://www.ediblewildfood.com/purslane.aspx

I haven’t tried foraging beyond some chanterelles last year. Since purslane is considered a weed, being sure it hasn’t been sprayed is essential. Foragers are very careful about that. Even state and national parks here are starting to use herbicides to control what they consider to be invasive. Another issue is that purslane is a great at bio-remediating chemicals like PCB’s, so you need to know the history of where you are foraging.
The other option is to grow your own purslane which might not be too difficult.
 
Well I bought some Finnish licorice candy yesterday. I don't know if it was the little coughing girl that chased me at the no-smoking park as I was trying to escape her father's second hand smoke :rolleyes: but I got a craving. It was delicious and no more itchy throat, psychosomatic or not. :) Here's one of those dangerous papers:
http://en.cnki.com.cn/Article_en/CJF...A200310014.htm

And, yes, licorice is not for everyone. I tried an extract many years ago and didn't like the effect for me. Even the candy and teas can go wrong in people without a history of high BP if enjoyed frequently for a couple of weeks.

https://www.fda.gov/consumers/consum...trick-or-treat

ETA: Better brush teeth right after enjoying licorice candy!
 
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