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Eur J Immunol
. 2020 May 21.
doi: 10.1002/eji.202048663. Online ahead of print.
COVID-19 Vaccines: Knowing the Unknown
Huibin Lv 1 , Nicholas C Wu 2 , Chris K P Mok 1
Affiliations
- PMID: 32437587
- DOI: 10.1002/eji.202048663
Abstract
Vaccine development against SARS-CoV-2 has drawn attention around the globe due to the exploding pandemic. Although COVID-19 is caused by a new coronavirus, SARS-CoV-2, previous research on other coronavirus vaccines, such as FIPV, SARS and MERS, has provided valuable information for the rapid development of COVID-19 vaccine. However, important knowledge gaps remain - some are specific to SARS-CoV-2, others are fundamental to immunology and vaccinology. Here we discuss areas that need to be addressed for COVID-19 vaccine development, and what can be learned from examples of vaccine development in the past. Since the beginning of the outbreak, the research progress on COVID-19 has been remarkable. We are therefore optimistic about the rapid development of COVID-19 vaccine. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; SARS-CoV-2; vaccine.
This article is protected by copyright. All rights reserved.