Br J Haematol
. 2020 Jul 6;10.1111/bjh.17003.
doi: 10.1111/bjh.17003. Online ahead of print.
Effect of low or high doses of low-molecular-weight heparin on thrombin generation and other haemostasis parameters in critically ill patients with COVID-19
Antonio Chistolini 1 , Franco Ruberto 2 , Francesco Alessandri 2 , Cristina Santoro 1 , Francesco Barone 1 , Maria Cristina Puzzolo 1 , Giancarlo Ceccarelli 3 , Maria L De Luca 1 , Massimo Mancone 4 , Domenico Alvaro 5 , Fabio M Pulcinelli 6 , Maurizio Martelli 1 , Robin Fo? 1 , Francesco Pugliese 2 , Policlinico Umberto I COVID‐19 Group
Collaborators, Affiliations
- PMID: 32779783
- PMCID: PMC7361613
- DOI: 10.1111/bjh.17003
Abstract
The clinical picture of the coronavirus 2 (SARS‐CoV‐2)/COVID‐19‐related acute respiratory syndrome is often associated with a coagulopathy. An elevated D‐dimer has been linked with an unfavorable prognosis in COVID‐19 patients.
Keywords: COVID‐19; low‐molecular‐weight heparin; thrombin generation assay