J Med Virol Compassionate Use of hzVSF-v13 in Two Patients With Severe COVID-19 - FluTrackers News and Information

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J Med Virol Compassionate Use of hzVSF-v13 in Two Patients With Severe COVID-19

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tetano

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J Med Virol Compassionate Use of hzVSF-v13 in Two Patients With Severe COVID-19

May 27, 2020, 09:40 AM

J Med Virol

. 2020 May 26.
doi: 10.1002/jmv.26063. Online ahead of print.
Compassionate Use of hzVSF-v13 in Two Patients With Severe COVID-19

Chang Kyung Kang¹, Pyoeng Gyun Choe¹, Sungman Park², Taek Soo Kim³, Moon-Woo Seong³, Nam-Joong Kim¹, Myoung-Don Oh¹, Wan Beom Park¹, Yoon-Won Kim²

Affiliations
PMID: 32458425

DOI: 10.1002/jmv.26063

Abstract

We report the compassionate use of humanized Virus Suppressing Factor-variant 13 (hzVSF-v13) in two patients with severe coronavirus disease 2019 (COVID-19) pneumonia. Both patients, including an 81-year-old man who required extracorporeal membrane oxygenation, showed clinical improvement. These results warrant placebo-controlled trials to evaluate the hzVSF-v13 efficacy against COVID-19. This article is protected by copyright. All rights reserved.

Keywords: COVID-19; SARS-CoV-2; antiviral agents; hzVSF-v13.

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