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Clin Lab Med. 2010 Mar;30(1):1-20.
Avian Influenza A H5N1 Virus.
Loeffelholz MJ.
Clinical Microbiology Division, Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0740, USA.
Abstract
Although influenza A viruses of avian origin have long been responsible for influenza pandemics, including the "Spanish flu" pandemic of 1918, human infections caused by avian subtypes of influenza A virus, most notably H5N1, have emerged since the 1990s (H5N1 in 1997; H9N2 in 1999; and H7N7 in 2003). The wide geographic distribution of influenza A H5N1 in avian species, and the number and severity of human infections are unprecedented. Together with the ongoing genetic evolution of this virus, these features make influenza A H5N1 a likely candidate for a future influenza pandemic. This article discusses the epidemiology, pathogenesis, and diagnosis of human infections caused by influenza A H5N1 virus. Copyright ? 2010 Elsevier Inc. All rights reserved.
PMID: 20513539 [PubMed - as supplied by publisher]
Avian Influenza A H5N1 Virus.
Loeffelholz MJ.
Clinical Microbiology Division, Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0740, USA.
Abstract
Although influenza A viruses of avian origin have long been responsible for influenza pandemics, including the "Spanish flu" pandemic of 1918, human infections caused by avian subtypes of influenza A virus, most notably H5N1, have emerged since the 1990s (H5N1 in 1997; H9N2 in 1999; and H7N7 in 2003). The wide geographic distribution of influenza A H5N1 in avian species, and the number and severity of human infections are unprecedented. Together with the ongoing genetic evolution of this virus, these features make influenza A H5N1 a likely candidate for a future influenza pandemic. This article discusses the epidemiology, pathogenesis, and diagnosis of human infections caused by influenza A H5N1 virus. Copyright ? 2010 Elsevier Inc. All rights reserved.
PMID: 20513539 [PubMed - as supplied by publisher]
