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Emerg Infect Dis
. 2022 Jul 13;28(8).
doi: 10.3201/eid2808.220584. Online ahead of print.
Effectiveness of Naturally Acquired and Vaccine-Induced Immune Responses to SARS-CoV-2 Mu Variant
Edmilson F de Oliveira-Filho, Bladimiro Rincon-Orozco, Natalia Jones-Cifuentes, Brigitte Peña-López, Barbara Mühlemann, Christian Drosten, Andres Moreira-Soto, Jan Felix Drexler
- PMID: 35830278
- DOI: 10.3201/eid2808.220584
Abstract
SARS-CoV-2 Mu variant emerged in Colombia in 2021 and spread globally. In 49 serum samples from vaccinees and COVID-19 survivors in Colombia, neutralization was significantly lower (p<0.0001) for Mu than a parental strain and variants of concern. Only the Omicron variant of concern demonstrated higher immune evasion.
Keywords: COVID-19; Colombia; SARS-CoV-2; acquired immunity; coronavirus disease; immune evasion; neutralization; severe acute respiratory syndrome coronavirus; vaccine efficacy; virus variants; viruses.