New Microbes New Infect . A single nucleotide distinguishes the SARS-CoV-2 in the Wuhan outbreak in December 2019 from that in Beijing-Xinfadi in June 2020, China

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New Microbes New Infect


. 2020 Dec 15;39:100835.
doi: 10.1016/j.nmni.2020.100835. eCollection 2021 Jan.
A single nucleotide distinguishes the SARS-CoV-2 in the Wuhan outbreak in December 2019 from that in Beijing-Xinfadi in June 2020, China


Y-Q Pan ¹ , A N Bahoussi ¹ , F Guo ¹ , L Xing ^{1 2 3}



Affiliations

• PMID: 33425367
• PMCID: PMC7785950
• DOI: 10.1016/j.nmni.2020.100835

Free PMC article

Abstract

Two major locally transmitted outbreaks of coronavirus disease 2019 occurred in China, one in Wuhan from December 2019 to April 2020, another in Beijing-Xinfadi in June 2020. Severe acute respiratory syndrome coronavirus 2 isolated from these two outbreaks can be distinguished by a conserved pyrimidine nucleotide located at nucleotide position 241 in the 5'-untranslated region of the virus genome.

Keywords: 5′-untranslated region; Beijing; Wuhan; coronavirus disease 2019; pyrimidine.