Utility of Pandemic H1N1-09 Influenza Virus Recombinant Hemagglutinin Protein Based ELISA for Sero-Surveillance - FluTrackers News and Information

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Utility of Pandemic H1N1-09 Influenza Virus Recombinant Hemagglutinin Protein Based ELISA for Sero-Surveillance

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tetano

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Join Date: Dec 2009

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Utility of Pandemic H1N1-09 Influenza Virus Recombinant Hemagglutinin Protein Based ELISA for Sero-Surveillance

July 16, 2010, 11:35 AM

Clin Vaccine Immunol. 2010 Jul 14. [Epub ahead of print]
Utility of Pandemic H1N1-09 Influenza Virus Recombinant Hemagglutinin Protein Based ELISA for Sero-Surveillance.

Arankalle VA, Virkar RG, Tandale BV, Ingle NB.

National Institute of Virology, 130/1, Sus Road, Pashan, Pune, India, 411021.
Abstract

Comparison of an ELISA for the detection of IgG antibodies against pandemic-H1N1-09 influenza virus employing recombinant hemagglutinin protein of the virus and hemagglutination-inhibition (HI) employing 783 sera showed concordance of 98.4% suggesting utility of ELISA in sero-surveillance. 269 (100%) sera with >/= 20 HI titer were ELISA reactive.

PMID: 20631333 [PubMed - as supplied by publisher]

Utility of pandemic H1N1 2009 influenza virus recombinant hemagglutinin protein-based enzyme-linked immunosorbent assay for serosurveillance - PubMed

http://www.ncbi.nlm.nih.gov/pubmed/20631333

An enzyme-linked immunosorbent assay (ELISA) for the detection of IgG antibodies against the pandemic H1N1 2009 influenza A virus, employing a recombinant hemagglutinin protein of the virus, was compared to the hemagglutination inhibition (HI) test using 783 serum samples. The results showed a conco …

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