Announcement

Collapse
No announcement yet.

Rapid detection of respiratory organisms with the FilmArray respiratory panel in a large children's hospital in China

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Rapid detection of respiratory organisms with the FilmArray respiratory panel in a large children's hospital in China

    BMC Infect Dis. 2018 Oct 11;18(1):510. doi: 10.1186/s12879-018-3429-6.
    Rapid detection of respiratory organisms with the FilmArray respiratory panel in a large children's hospital in China.

    Li J1, Tao Y2, Tang M1, Du B1, Xia Y3, Mo X4, Cao Q5.
    Author information

    Abstract

    BACKGROUND:

    Respiratory tract infections (RTIs) are the most common illness in children, and rapid diagnosis is required for the optimal management of RTIs, especially severe infections.
    METHODS:

    Nasopharyngeal swab or sputum specimens were collected from children aged 19 days to 15 years who were admitted to a hospital in Shanghai and diagnosed with RTIs. The specimens were tested with the FilmArray Respiratory Panel, a multiplex PCR assay that detects 16 viruses, Mycoplasma pneumoniae (M. pneumoniae), Bordetella pertussis (B. pertussis) and Chlamydophila pneumoniae (C. pneumoniae).
    RESULTS:

    Among the 775 children studied, 626 (80.8%, 626/775) tested positive for at least one organism, and multiple organisms were detected in 198 (25.5%). Rhinoviruses/enteroviruses (25.5%, 198/775) were detected most often, followed by respiratory syncytial virus (19.5%, 151/775), parainfluenza virus 3 (14.8%, 115/775), influenza A or B (10.9%), adenovirus (10.8%), M. pneumoniae (10.6%) and B. pertussis (6.3%). The prevalence of organisms differed by age, and most of the viruses were more common in winter. Of the 140 children suspected of having pertussis, 35.0% (49/140) tested positive for B. pertussis.
    CONCLUSIONS:

    FilmArray RP allows the rapid simultaneous detection of a wide number of respiratory organisms, with limited hands-on time, in Chinese pediatric patients with RTIs.


    KEYWORDS:

    Children; FilmArray respiratory panel; Respiratory organisms; Respiratory tract infections

    PMID: 30305033 DOI: 10.1186/s12879-018-3429-6
    Free full text
Working...
X