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This week’s topics
1. Overview of respiratory virus epidemiology in the EU/EEA
2. SARS-CoV-2 variant classification
3. Mpox in the EU/EEA, Western Balkan countries and Türkiye – 2022–2025
4. Leprosy - Romania ex. Indonesia - 2025
5. Mpox clade Ib and clade IIb recombinant strain detected in UK traveller returning from Asia
6. Mpox due to monkeypox virus clades I and II – Global outbreak – 2024–2025
7. Marburg virus disease (MVD) - Ethiopia - 2025
8. Dengue – Multi-country (World) – Monitoring global outbreaks – Monthly update
9. Chikungunya virus disease – Multi-country (World) – Monitoring global outbreaks – Monthly
update
Executive summary
This marks the final weekly CDTR of 2025. Wishing you a joyful holiday season
filled with peace and happiness, and all the best for the year ahead!
Overview of respiratory virus epidemiology in the EU/EEA
• The number of patients presenting to primary care with symptoms of respiratory illness is
elevated in approximately half of the reporting countries. This indicates that there is currently
significant respiratory virus circulation in the European Union/European Economic Area
(EU/EEA).
• Influenza virus circulation continues to increase, with most countries now reporting
widespread activity at low-to-medium intensity. Influenza A is dominant in all countries, with
A(H3N2) driving the increasing trend in recent weeks. Circulation is highest in children aged 5–
14 years. Increases in hospitalisation are being observed in some countries, affecting all age
groups, but primarily in adults aged 65 years and above.
European Centre for Disease Prevention and Control, Solna, Sweden
Classified as ECDC NORMALSURVEILLANCE REPORT
Weekly Communicable Disease Threats Report, Week 51, 13–19 December 2025
• Influenza activity increased three to four weeks earlier than in the previous two seasons.
ECDC’s Threat Assessment Brief assessing the risk of influenza for the EU/EEA in the context of
increasing circulation of A(H3N2) subclade K outlines key recommendations including
vaccination, use of antivirals, use of face masks in healthcare and long-term care facilities, and
healthcare preparedness. These recommendations should be carefully considered and
implemented promptly, given the current epidemiological situation and the approaching festive
period.
• Respiratory syncytial virus (RSV)
Continued: https://www.ecdc.europa.eu/sites/def...ek-51-2025.pdf