Inovio Pharmaceuticals' Synthetic Avian Flu Vaccine Demonstrates Inhibition of Multiple H5N1 Strains in Phase I Trial

[tetano]

BLUE BELL, Pa., Nov. 17, 2011 /PRNewswire/ -- Inovio Pharmaceuticals, Inc. (NYSE AMEX: INO), which is advancing synthetic vaccines to fight cancers and infectious diseases, announced today that a single intradermal (ID) electroporation boost of its SynCon? avian influenza vaccine generated HAI titers against six different, unmatched strains of H5N1 - a distinct new clinical achievement on the global research community's path to develop universal influenza vaccines. This single synthetic vaccine generated a four-fold or greater rise in hemagglutination inhibition (HAI) titers in 50% of boosted subjects in its Phase I clinical study. These results were presented at the 5th WHO Meeting on Influenza Vaccines that Induce Broad Spectrum and Long-Lasting Immune Responses by Dr. Niranjan Sardesai, Inovio's Sr. VP, Research and Development. The invitation-only meeting showcased development programs progressing towards broadly cross-reactive flu vaccines.

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